Traditional models of Parkinson’s disease (PD) focus on events at the neuronal synapse and although recently, non-synaptic pathways have been linked to PD, most therapies still target the synapse. Large-scale Genome Wide Association Studies (GWAS), mRNA array analyses and neuronal proteomics give new insights into causal and pathological mechanisms at all levels: genes – transcripts – proteins. Here we examined correlations amongst different datasets, specifically looking for evidence of synaptic mechanisms involved in PD.
|Publication status||Published - 19 Jun 2016|
|Event||20th International Congress of Parkinson's Disease and Movement Disorders - Berlin, Germany|
Duration: 19 Jun 2016 → 23 Jun 2016
|Conference||20th International Congress of Parkinson's Disease and Movement Disorders|
|Period||19/06/16 → 23/06/16|
- Multidisciplinary Approach