Abstract / Description of output
Traditional models of Parkinson’s disease (PD) focus on events at the neuronal synapse and although recently, non-synaptic pathways have been linked to PD, most therapies still target the synapse. Large-scale Genome Wide Association Studies (GWAS), mRNA array analyses and neuronal proteomics give new insights into causal and pathological mechanisms at all levels: genes – transcripts – proteins. Here we examined correlations amongst different datasets, specifically looking for evidence of synaptic mechanisms involved in PD.
Original language | English |
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Publication status | Published - 19 Jun 2016 |
Event | 20th International Congress of Parkinson's Disease and Movement Disorders - Berlin, Germany Duration: 19 Jun 2016 → 23 Jun 2016 |
Conference
Conference | 20th International Congress of Parkinson's Disease and Movement Disorders |
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Country/Territory | Germany |
Period | 19/06/16 → 23/06/16 |
Keywords / Materials (for Non-textual outputs)
- Multidisciplinary Approach