Tailing off: PABP and CNOT generate cycles of mRNA deadenylation

Stefan Bresson; David Tollervey

doi:10.1016/j.molcel.2018.06.009

Tailing off: PABP and CNOT generate cycles of mRNA deadenylation

Stefan Bresson, David Tollervey^*

^*Corresponding author for this work

School of Biological Sciences

Research output: Contribution to journal › Short survey › peer-review

Abstract / Description of output

In this issue of Molecular Cell, Webster et al. (2018) and Yi et al. (2018) dissect the mechanisms underlying cytoplasmic mRNA deadenylation by the Ccr4-Not (CNOT) complex. Crucial to this process is the poly(A) binding protein Pab1/PABPC1, which both stimulates and suppresses the activity of different deadenylases. In this issue of Molecular Cell, Webster et al. (2018) and Yi et al. (2018) dissect the mechanisms underlying cytoplasmic mRNA deadenylation by the Ccr4-Not (CNOT) complex. Crucial to this process is the poly(A) binding protein Pab1/PABPC1, which both stimulates and suppresses the activity of different deadenylases.

Original language	English
Pages (from-to)	987-988
Number of pages	2
Journal	Molecular Cell
Volume	70
Issue number	6
DOIs	https://doi.org/10.1016/j.molcel.2018.06.009
Publication status	E-pub ahead of print - 21 Jun 2018

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10.1016/j.molcel.2018.06.009

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@article{a62825bd2fa34362bd5e2fbc6b9b4aeb,

title = "Tailing off: PABP and CNOT generate cycles of mRNA deadenylation",

abstract = "In this issue of Molecular Cell, Webster et al. (2018) and Yi et al. (2018) dissect the mechanisms underlying cytoplasmic mRNA deadenylation by the Ccr4-Not (CNOT) complex. Crucial to this process is the poly(A) binding protein Pab1/PABPC1, which both stimulates and suppresses the activity of different deadenylases. In this issue of Molecular Cell, Webster et al. (2018) and Yi et al. (2018) dissect the mechanisms underlying cytoplasmic mRNA deadenylation by the Ccr4-Not (CNOT) complex. Crucial to this process is the poly(A) binding protein Pab1/PABPC1, which both stimulates and suppresses the activity of different deadenylases.",

author = "Stefan Bresson and David Tollervey",

year = "2018",

month = jun,

day = "21",

doi = "10.1016/j.molcel.2018.06.009",

language = "English",

volume = "70",

pages = "987--988",

journal = "Molecular Cell",

issn = "1097-2765",

publisher = "Cell Press",

number = "6",

}

TY - JOUR

T1 - Tailing off

T2 - PABP and CNOT generate cycles of mRNA deadenylation

AU - Bresson, Stefan

AU - Tollervey, David

PY - 2018/6/21

Y1 - 2018/6/21

N2 - In this issue of Molecular Cell, Webster et al. (2018) and Yi et al. (2018) dissect the mechanisms underlying cytoplasmic mRNA deadenylation by the Ccr4-Not (CNOT) complex. Crucial to this process is the poly(A) binding protein Pab1/PABPC1, which both stimulates and suppresses the activity of different deadenylases. In this issue of Molecular Cell, Webster et al. (2018) and Yi et al. (2018) dissect the mechanisms underlying cytoplasmic mRNA deadenylation by the Ccr4-Not (CNOT) complex. Crucial to this process is the poly(A) binding protein Pab1/PABPC1, which both stimulates and suppresses the activity of different deadenylases.

AB - In this issue of Molecular Cell, Webster et al. (2018) and Yi et al. (2018) dissect the mechanisms underlying cytoplasmic mRNA deadenylation by the Ccr4-Not (CNOT) complex. Crucial to this process is the poly(A) binding protein Pab1/PABPC1, which both stimulates and suppresses the activity of different deadenylases. In this issue of Molecular Cell, Webster et al. (2018) and Yi et al. (2018) dissect the mechanisms underlying cytoplasmic mRNA deadenylation by the Ccr4-Not (CNOT) complex. Crucial to this process is the poly(A) binding protein Pab1/PABPC1, which both stimulates and suppresses the activity of different deadenylases.

UR - http://www.scopus.com/inward/record.url?scp=85048582140&partnerID=8YFLogxK

U2 - 10.1016/j.molcel.2018.06.009

DO - 10.1016/j.molcel.2018.06.009

M3 - Short survey

AN - SCOPUS:85048582140

SN - 1097-2765

VL - 70

SP - 987

EP - 988

JO - Molecular Cell

JF - Molecular Cell

IS - 6

ER -

Tailing off: PABP and CNOT generate cycles of mRNA deadenylation

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Nuclear RNA processing and surveillance

Life through a Lens

Core funding renewal for the Wellcome Trust Centre for Cell Biology

Cite this

Tailing off: PABP and CNOT generate cycles of mRNA deadenylation

Abstract / Description of output

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Other files and links

Fingerprint

Projects

Nuclear RNA processing and surveillance

Life through a Lens

Core funding renewal for the Wellcome Trust Centre for Cell Biology

Cite this