Abstract
The ZR-75-1 ER positive breast cancer cell line, xenografted in female nude mice, has been used to determine the effect of tamoxifen on cell proliferation (as measured by mitosis) and cell death (as evidenced by apoptosis and necrosis). After 2 days treatment, there was a significant rise in apoptosis (p
Original language | English |
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Pages (from-to) | 99-107 |
Number of pages | 9 |
Journal | Breast cancer research and treatment |
Volume | 45 |
Issue number | 2 |
Publication status | Published - Sep 1997 |
Keywords
- Animals
- Antineoplastic Agents, Hormonal
- Apoptosis
- Breast Neoplasms
- Cell Division
- Female
- Mice
- Mice, Nude
- Mitotic Index
- Neoplasm Transplantation
- Tamoxifen
- Time Factors
- Transplantation, Heterologous
- Tumor Cells, Cultured