Tamoxifen induced apoptosis in ZR-75 breast cancer xenografts antedates tumour regression

D A Cameron; A A Ritchie; S Langdon; T J Anderson; W R Miller

Tamoxifen induced apoptosis in ZR-75 breast cancer xenografts antedates tumour regression

D A Cameron, A A Ritchie, S Langdon, T J Anderson, W R Miller

Research output: Contribution to journal › Article › peer-review

Abstract

The ZR-75-1 ER positive breast cancer cell line, xenografted in female nude mice, has been used to determine the effect of tamoxifen on cell proliferation (as measured by mitosis) and cell death (as evidenced by apoptosis and necrosis). After 2 days treatment, there was a significant rise in apoptosis (p

Original language	English
Pages (from-to)	99-107
Number of pages	9
Journal	Breast cancer research and treatment
Volume	45
Issue number	2
Publication status	Published - Sep 1997

Keywords

Animals
Antineoplastic Agents, Hormonal
Apoptosis
Breast Neoplasms
Cell Division
Female
Mice
Mice, Nude
Mitotic Index
Neoplasm Transplantation
Tamoxifen
Time Factors
Transplantation, Heterologous
Tumor Cells, Cultured

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title = "Tamoxifen induced apoptosis in ZR-75 breast cancer xenografts antedates tumour regression",

abstract = "The ZR-75-1 ER positive breast cancer cell line, xenografted in female nude mice, has been used to determine the effect of tamoxifen on cell proliferation (as measured by mitosis) and cell death (as evidenced by apoptosis and necrosis). After 2 days treatment, there was a significant rise in apoptosis (p ",

keywords = "Animals, Antineoplastic Agents, Hormonal, Apoptosis, Breast Neoplasms, Cell Division, Female, Mice, Mice, Nude, Mitotic Index, Neoplasm Transplantation, Tamoxifen, Time Factors, Transplantation, Heterologous, Tumor Cells, Cultured",

author = "Cameron, {D A} and Ritchie, {A A} and S Langdon and Anderson, {T J} and Miller, {W R}",

year = "1997",

month = sep,

language = "English",

volume = "45",

pages = "99--107",

journal = "Breast cancer research and treatment",

issn = "0167-6806",

publisher = "Springer New York",

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T1 - Tamoxifen induced apoptosis in ZR-75 breast cancer xenografts antedates tumour regression

AU - Cameron, D A

AU - Ritchie, A A

AU - Langdon, S

AU - Anderson, T J

AU - Miller, W R

PY - 1997/9

Y1 - 1997/9

N2 - The ZR-75-1 ER positive breast cancer cell line, xenografted in female nude mice, has been used to determine the effect of tamoxifen on cell proliferation (as measured by mitosis) and cell death (as evidenced by apoptosis and necrosis). After 2 days treatment, there was a significant rise in apoptosis (p

AB - The ZR-75-1 ER positive breast cancer cell line, xenografted in female nude mice, has been used to determine the effect of tamoxifen on cell proliferation (as measured by mitosis) and cell death (as evidenced by apoptosis and necrosis). After 2 days treatment, there was a significant rise in apoptosis (p

KW - Animals

KW - Antineoplastic Agents, Hormonal

KW - Apoptosis

KW - Breast Neoplasms

KW - Cell Division

KW - Female

KW - Mice

KW - Mice, Nude

KW - Mitotic Index

KW - Neoplasm Transplantation

KW - Tamoxifen

KW - Time Factors

KW - Transplantation, Heterologous

KW - Tumor Cells, Cultured

M3 - Article

C2 - 9342435

VL - 45

SP - 99

EP - 107

JO - Breast cancer research and treatment

JF - Breast cancer research and treatment

SN - 0167-6806

IS - 2

ER -