Targeting of HIF-alpha  to the von Hippel-Lindau Ubiquitylation Complex by O2-Regulated Prolyl Hydroxylation

P. Jaakkola; D. R. Mole; Y.-m. Tian; M. I. Wilson; J. Gielbert; S. J. Gaskell; Alex Von Kriegsheim; H. F. Hebestreit; M. Mukherji; C. J. Schofield; P. H. Maxwell; C. W. Pugh; P. J. Ratcliffe

doi:10.1126/science.1059796

Targeting of HIF-alpha to the von Hippel-Lindau Ubiquitylation Complex by O2-Regulated Prolyl Hydroxylation

P. Jaakkola, D. R. Mole, Y.-m. Tian, M. I. Wilson, J. Gielbert, S. J. Gaskell, Alex Von Kriegsheim, H. F. Hebestreit, M. Mukherji, C. J. Schofield, P. H. Maxwell, C. W. Pugh, P. J. Ratcliffe

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	468-472
Journal	Science
Volume	292
Issue number	5516
DOIs	https://doi.org/10.1126/science.1059796
Publication status	Published - 20 Apr 2001

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10.1126/science.1059796

http://www.sciencemag.org/cgi/doi/10.1126/science.1059796

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Jaakkola, P., Mole, D. R., Tian, Y., Wilson, M. I., Gielbert, J., Gaskell, S. J., Von Kriegsheim, A., Hebestreit, H. F., Mukherji, M., Schofield, C. J., Maxwell, P. H., Pugh, C. W., & Ratcliffe, P. J. (2001). Targeting of HIF-alpha to the von Hippel-Lindau Ubiquitylation Complex by O2-Regulated Prolyl Hydroxylation. Science, 292(5516), 468-472. https://doi.org/10.1126/science.1059796

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title = "Targeting of HIF-alpha to the von Hippel-Lindau Ubiquitylation Complex by O2-Regulated Prolyl Hydroxylation",

author = "P. Jaakkola and Mole, {D. R.} and Y.-m. Tian and Wilson, {M. I.} and J. Gielbert and Gaskell, {S. J.} and {Von Kriegsheim}, Alex and Hebestreit, {H. F.} and M. Mukherji and Schofield, {C. J.} and Maxwell, {P. H.} and Pugh, {C. W.} and Ratcliffe, {P. J.}",

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Jaakkola, P, Mole, DR, Tian, Y, Wilson, MI, Gielbert, J, Gaskell, SJ, Von Kriegsheim, A, Hebestreit, HF, Mukherji, M, Schofield, CJ, Maxwell, PH, Pugh, CW & Ratcliffe, PJ 2001, 'Targeting of HIF-alpha to the von Hippel-Lindau Ubiquitylation Complex by O2-Regulated Prolyl Hydroxylation', Science, vol. 292, no. 5516, pp. 468-472. https://doi.org/10.1126/science.1059796

TY - JOUR

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AU - Jaakkola, P.

AU - Mole, D. R.

AU - Tian, Y.-m.

AU - Wilson, M. I.

AU - Gielbert, J.

AU - Gaskell, S. J.

AU - Von Kriegsheim, Alex

AU - Hebestreit, H. F.

AU - Mukherji, M.

AU - Schofield, C. J.

AU - Maxwell, P. H.

AU - Pugh, C. W.

AU - Ratcliffe, P. J.

PY - 2001/4/20

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U2 - 10.1126/science.1059796

DO - 10.1126/science.1059796

M3 - Article

SN - 0036-8075

VL - 292

SP - 468

EP - 472

JO - Science

JF - Science

IS - 5516

ER -