The antiestrogen ICI 182,780 decreases the expression of estrogen receptor-alpha but has no effect on estrogen receptor-beta and androgen receptor in rat efferent ductules

Cleida A Oliveira, Rong Nie, Kay Carnes, Luiz R Franca, Gail S Prins, Philippa T K Saunders, Rex A Hess

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

The antiestrogen ICI 182,780 has been used successfully as an alternative experimental model for the study of estrogen action in the rodent adult male reproductive tract. Although ICI 182,780 causes severe alterations in testicular and efferent ductule morphology and function, the effects on the expression of estrogen and androgen receptors in the male have not been shown.
Original languageEnglish
Pages (from-to)75
JournalReproductive Biology and Endocrinology
Volume1
DOIs
Publication statusPublished - 2003

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