The application of fixed hydrophobic patterns for confinement of aqueous solutions in proteomic microarrays

Y. Li, E. O. McKenna, W. Parkes, A. R. Pitt, Anthony Walton

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A protein microarray hybridisation system has been implemented by employing patterned hydrophobic thin films on hydrophilic substrates as a means of confinement for aqueous samples. This approach has the ability to handle, and keep separate, small sample volumes of just a few microlitres. In addition, the system is more straightforward to use than the existing multi-well gasket solution. The paper describes the fabrication method and the system is demonstrated for a model protein microarray assay. (C) 2011 American Institute of Physics. [doi:10.1063/1.3626037]

Original languageEnglish
Article number073703
Pages (from-to)-
Number of pages3
JournalApplied Physics Letters
Issue number7
Publication statusPublished - 15 Aug 2011


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