The application of fixed hydrophobic patterns for confinement of aqueous solutions in proteomic microarrays

Y. Li; E. O. McKenna; W. Parkes; A. R. Pitt; Anthony Walton

doi:10.1063/1.3626037

The application of fixed hydrophobic patterns for confinement of aqueous solutions in proteomic microarrays

Y. Li, E. O. McKenna, W. Parkes, A. R. Pitt, Anthony Walton

School of Engineering

Research output: Contribution to journal › Article › peer-review

Abstract

A protein microarray hybridisation system has been implemented by employing patterned hydrophobic thin films on hydrophilic substrates as a means of confinement for aqueous samples. This approach has the ability to handle, and keep separate, small sample volumes of just a few microlitres. In addition, the system is more straightforward to use than the existing multi-well gasket solution. The paper describes the fabrication method and the system is demonstrated for a model protein microarray assay. (C) 2011 American Institute of Physics. [doi:10.1063/1.3626037]

Original language	English
Article number	073703
Pages (from-to)	-
Number of pages	3
Journal	Applied Physics Letters
Volume	99
Issue number	7
DOIs	https://doi.org/10.1063/1.3626037
Publication status	Published - 15 Aug 2011

Keywords / Materials (for Non-textual outputs)

PROTEIN MICROARRAYS
FLOW

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10.1063/1.3626037

Cite this

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abstract = "A protein microarray hybridisation system has been implemented by employing patterned hydrophobic thin films on hydrophilic substrates as a means of confinement for aqueous samples. This approach has the ability to handle, and keep separate, small sample volumes of just a few microlitres. In addition, the system is more straightforward to use than the existing multi-well gasket solution. The paper describes the fabrication method and the system is demonstrated for a model protein microarray assay. (C) 2011 American Institute of Physics. [doi:10.1063/1.3626037]",

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AU - Li, Y.

AU - McKenna, E. O.

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AU - Pitt, A. R.

AU - Walton, Anthony

PY - 2011/8/15

Y1 - 2011/8/15

N2 - A protein microarray hybridisation system has been implemented by employing patterned hydrophobic thin films on hydrophilic substrates as a means of confinement for aqueous samples. This approach has the ability to handle, and keep separate, small sample volumes of just a few microlitres. In addition, the system is more straightforward to use than the existing multi-well gasket solution. The paper describes the fabrication method and the system is demonstrated for a model protein microarray assay. (C) 2011 American Institute of Physics. [doi:10.1063/1.3626037]

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KW - FLOW

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The application of fixed hydrophobic patterns for confinement of aqueous solutions in proteomic microarrays

Abstract

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RASOR-Radical Solutions for Researching the Proteome: Interdisciplinary Research Collaboration in proteomic technologies

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The application of fixed hydrophobic patterns for confinement of aqueous solutions in proteomic microarrays

Abstract

Keywords / Materials (for Non-textual outputs)

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RASOR-Radical Solutions for Researching the Proteome: Interdisciplinary Research Collaboration in proteomic technologies

Cite this