Projects per year
METHODS: A systematic review and meta-analysis was carried out to assess the measurement of retinal properties in dementia using fundus imaging.
RESULTS: Ten studies assessing retinal properties in dementia were included. Quantitative measurement revealed significant yet inconsistent pathologic changes in vessel caliber, tortuosity and fractal dimension. Retinopathy was more prevalent in dementia. No association of age-related macular degeneration with dementia was reported.
DISCUSSION: Inconsistent findings across studies provides tentative support for the application of fundus camera imaging as a means of identifying changes associated with dementia. The potential of fundus image analysis in differentiating between dementia subtypes should be investigated using larger well characterised samples. Future work should focus on refining and standardising methods and measurements.
|Journal||Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring|
|Early online date||2 Dec 2016|
|Publication status||Published - 2017|
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- 2 Finished
30/04/15 → 28/08/18