The assignment of the genes coding for human complement components C6 and C7 to chromosome 5

S J Jeremiah; C M Abbott; Z Murad; S Povey; H J Thomas; E Solomon; R G DiScipio; G H Fey

The assignment of the genes coding for human complement components C6 and C7 to chromosome 5

S J Jeremiah, C M Abbott, Z Murad, S Povey, H J Thomas, E Solomon, R G DiScipio, G H Fey

Deanery of Molecular, Genetic and Population Health Sciences

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

A panel of 19 somatic cell hybrids was tested for the presence of human sequences coding for complement components C6 and C7 by restriction enzyme digestion and Southern blots probed with human C6 and C7 cDNA probes. C7 was also detected by amplifying part of the human gene in hybrid DNA using the polymerase chain reaction. Detection of human C6 and C7 was completely correlated with the presence of chromosome 5.

Original language	English
Pages (from-to)	141-7
Number of pages	7
Journal	Annals of Human Genetics
Volume	54
Issue number	Pt 2
Publication status	Published - 1990

Keywords / Materials (for Non-textual outputs)

Animals
Base Sequence
Blotting, Southern
Chromosome Mapping
Chromosomes, Human, Pair 5
Complement C6
Complement C7
Cricetinae
DNA Probes
Genes
Humans
Hybrid Cells
Molecular Sequence Data
Polymerase Chain Reaction

Cite this

@article{6e9e3f7d027544b18423144f31e4ce07,

title = "The assignment of the genes coding for human complement components C6 and C7 to chromosome 5",

abstract = "A panel of 19 somatic cell hybrids was tested for the presence of human sequences coding for complement components C6 and C7 by restriction enzyme digestion and Southern blots probed with human C6 and C7 cDNA probes. C7 was also detected by amplifying part of the human gene in hybrid DNA using the polymerase chain reaction. Detection of human C6 and C7 was completely correlated with the presence of chromosome 5.",

keywords = "Animals, Base Sequence, Blotting, Southern, Chromosome Mapping, Chromosomes, Human, Pair 5, Complement C6, Complement C7, Cricetinae, DNA Probes, Genes, Humans, Hybrid Cells, Molecular Sequence Data, Polymerase Chain Reaction",

author = "Jeremiah, {S J} and Abbott, {C M} and Z Murad and S Povey and Thomas, {H J} and E Solomon and DiScipio, {R G} and Fey, {G H}",

year = "1990",

language = "English",

volume = "54",

pages = "141--7",

journal = "Annals of Human Genetics",

issn = "0003-4800",

publisher = "Wiley-Blackwell",

number = "Pt 2",

}

TY - JOUR

T1 - The assignment of the genes coding for human complement components C6 and C7 to chromosome 5

AU - Jeremiah, S J

AU - Abbott, C M

AU - Murad, Z

AU - Povey, S

AU - Thomas, H J

AU - Solomon, E

AU - DiScipio, R G

AU - Fey, G H

PY - 1990

Y1 - 1990

N2 - A panel of 19 somatic cell hybrids was tested for the presence of human sequences coding for complement components C6 and C7 by restriction enzyme digestion and Southern blots probed with human C6 and C7 cDNA probes. C7 was also detected by amplifying part of the human gene in hybrid DNA using the polymerase chain reaction. Detection of human C6 and C7 was completely correlated with the presence of chromosome 5.

AB - A panel of 19 somatic cell hybrids was tested for the presence of human sequences coding for complement components C6 and C7 by restriction enzyme digestion and Southern blots probed with human C6 and C7 cDNA probes. C7 was also detected by amplifying part of the human gene in hybrid DNA using the polymerase chain reaction. Detection of human C6 and C7 was completely correlated with the presence of chromosome 5.

KW - Animals

KW - Base Sequence

KW - Blotting, Southern

KW - Chromosome Mapping

KW - Chromosomes, Human, Pair 5

KW - Complement C6

KW - Complement C7

KW - Cricetinae

KW - DNA Probes

KW - Genes

KW - Humans

KW - Hybrid Cells

KW - Molecular Sequence Data

KW - Polymerase Chain Reaction

M3 - Article

C2 - 2382968

SN - 0003-4800

VL - 54

SP - 141

EP - 147

JO - Annals of Human Genetics

JF - Annals of Human Genetics

IS - Pt 2

ER -

The assignment of the genes coding for human complement components C6 and C7 to chromosome 5

Abstract / Description of output

Keywords / Materials (for Non-textual outputs)

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