The association of smoking status with glycemic control, metabolic profile and diabetic complications: Results of the Australian National Diabetes Audit (ANDA).

N Szwarcbard, M Villani, A Earnest, S Andrikopoulos, N Wischer, G Soldatos, Danijela Gasevic, Sophia Zoungas

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Tobacco smoking and diabetes mellitus contribute significantly to the overall health burden and mortality of Australians. We aimed to assess the relationship of smoking with glycemic control, metabolic profile and complications in Australian patients living with diabetes. Methods: We analysed the 2011-2017 biennial Australian National Diabetes Audit cross-sectional data. Patients were classified as current, past or never smokers. Linear (or quantile) and logistic regression models were used to assess for associations. Results: Data from 15,352 patients were analysed, including 72.2% with type 2 diabetes. Current smokers comprised 13.5% of the study population. Current and past smokers had a median HbA1c that was 0.49% and 0.14% higher than never smokers, respectively, as well as higher triglyceride and lower HDL levels (p <0.0001 for all). Compared to never smokers, current smokers had higher odds of severe hypoglycaemia and current and past smokers had higher odds of myocardial infarction, stroke, peripheral vascular disease, lower limb amputation, erectile dysfunction and peripheral neuropathy (all p values ≤0.001), with no significant change over time. Conclusion: When compared to never smokers, current and past smokers had poorer glycemic and lipid control and higher odds of macrovascular and microvascular complications
Original languageEnglish
JournalJournal of Diabetes and its Complications
Early online date20 May 2020
DOIs
Publication statusE-pub ahead of print - 20 May 2020

Fingerprint Dive into the research topics of 'The association of smoking status with glycemic control, metabolic profile and diabetic complications: Results of the Australian National Diabetes Audit (ANDA).'. Together they form a unique fingerprint.

Cite this