The automatic annotation of bacterial genomes

Emily Richardson, Mick Watson

Research output: Contribution to journalArticlepeer-review


With the development of ultra-high-throughput technologies, the cost of sequencing bacterial genomes has been vastly reduced. As more genomes are sequenced, less time can be spent manually annotating those genomes, resulting in an increased reliance on automatic annotation pipelines. However, automatic pipelines can produce inaccurate genome annotation and their results often require manual curation. Here, we discuss the automatic and manual annotation of bacterial genomes, identify common problems introduced by the current genome annotation process and suggests potential solutions.
Original languageEnglish
Pages (from-to)1-12
JournalBriefings in bioinformatics
Issue number1
Early online date9 Mar 2012
Publication statusPublished - 2013


Dive into the research topics of 'The automatic annotation of bacterial genomes'. Together they form a unique fingerprint.

Cite this