The baseline characteristics and interim analyses of the high-risk sentinel cohort of the Vietnam Initiative on Zoonotic InfectiONS (VIZIONS)

Juan J. Carrique-Mas; Ngo T. Tue; Juliet E. Bryant; Karen Saylors; Nguyen V. Cuong; Ngo T. Hoa; Nguyen N. An; Vo B. Hien; Pham V. Lao; Nguyen C. Tu; Nguyen K. Chuyen; Nguyen T. K. Chuc; Dinh V. Tan; Hoang Van V. Duong; Tran K. Toan; Nguyen T. Y. Chi; James Campbell; Maia A. Rabaa; Behzad Nadjm; Mark Woolhouse; Heiman Wertheim; Guy Thwaites; Stephen Baker

doi:10.1038/srep17965

The baseline characteristics and interim analyses of the high-risk sentinel cohort of the Vietnam Initiative on Zoonotic InfectiONS (VIZIONS)

Juan J. Carrique-Mas^*, Ngo T. Tue, Juliet E. Bryant, Karen Saylors, Nguyen V. Cuong, Ngo T. Hoa, Nguyen N. An, Vo B. Hien, Pham V. Lao, Nguyen C. Tu, Nguyen K. Chuyen, Nguyen T. K. Chuc, Dinh V. Tan, Hoang Van V. Duong, Tran K. Toan, Nguyen T. Y. Chi, James Campbell, Maia A. Rabaa, Behzad Nadjm, Mark WoolhouseHeiman Wertheim, Guy Thwaites, Stephen Baker

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

The Vietnam Initiative for Zoonotic Infections (VIZIONS) includes community-based 'high-risk sentinel cohort' (HRSC) studies investigating individuals at risk of zoonotic infection due to occupational or residential exposure to animals. A total of 852 HRSC members were recruited between March 2013 and August 2014 from three provinces (Ha Noi, Dak Lak, and Dong Thap). The most numerous group (72.8%) corresponded to individuals living on farms, followed by slaughterers (16.3%) and animal health workers (8.5%). Nasal/pharyngeal and rectal swabs were collected from HRSC members at recruitment and after notifying illness. Exposure to exotic animals (including wild pigs, porcupine, monkey, civet, bamboo rat and bat) was highest for the Dak Lak cohort (53.7%), followed by Ha Noi (13.7%) and Dong Thap (4.0%). A total of 26.8% of individuals reported consumption of raw blood over the previous year; 33.6% slaughterers reported no use of protective equipment at work. Over 686 person-years of observation, 213 episodes of suspect infectious disease were notified, equivalent of 0.35 reports per person-year. Responsive samples were collected from animals in the farm cohort. There was noticeable time and space clustering of disease episodes suggesting that the VIZIONS set up is also suitable for the formal epidemiological investigation of disease outbreaks.

Original language	English
Article number	17965
Number of pages	10
Journal	Scientific Reports
Volume	5
DOIs	https://doi.org/10.1038/srep17965
Publication status	Published - 10 Dec 2015

Keywords / Materials (for Non-textual outputs)

CONSUMPTION

Access to Document

10.1038/srep17965

srep17965
This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
Final published version, 464 KBLicence: Creative Commons: Attribution (CC-BY)

Cite this

Carrique-Mas, J. J., Tue, N. T., Bryant, J. E., Saylors, K., Cuong, N. V., Hoa, N. T., An, N. N., Hien, V. B., Lao, P. V., Tu, N. C., Chuyen, N. K., Chuc, N. T. K., Tan, D. V., Duong, H. V. V., Toan, T. K., Chi, N. T. Y., Campbell, J., Rabaa, M. A., Nadjm, B., ... Baker, S. (2015). The baseline characteristics and interim analyses of the high-risk sentinel cohort of the Vietnam Initiative on Zoonotic InfectiONS (VIZIONS). Scientific Reports, 5, Article 17965. https://doi.org/10.1038/srep17965

@article{55782fed220e494d91d136e8c5ac0f38,

title = "The baseline characteristics and interim analyses of the high-risk sentinel cohort of the Vietnam Initiative on Zoonotic InfectiONS (VIZIONS)",

abstract = "The Vietnam Initiative for Zoonotic Infections (VIZIONS) includes community-based 'high-risk sentinel cohort' (HRSC) studies investigating individuals at risk of zoonotic infection due to occupational or residential exposure to animals. A total of 852 HRSC members were recruited between March 2013 and August 2014 from three provinces (Ha Noi, Dak Lak, and Dong Thap). The most numerous group (72.8%) corresponded to individuals living on farms, followed by slaughterers (16.3%) and animal health workers (8.5%). Nasal/pharyngeal and rectal swabs were collected from HRSC members at recruitment and after notifying illness. Exposure to exotic animals (including wild pigs, porcupine, monkey, civet, bamboo rat and bat) was highest for the Dak Lak cohort (53.7%), followed by Ha Noi (13.7%) and Dong Thap (4.0%). A total of 26.8% of individuals reported consumption of raw blood over the previous year; 33.6% slaughterers reported no use of protective equipment at work. Over 686 person-years of observation, 213 episodes of suspect infectious disease were notified, equivalent of 0.35 reports per person-year. Responsive samples were collected from animals in the farm cohort. There was noticeable time and space clustering of disease episodes suggesting that the VIZIONS set up is also suitable for the formal epidemiological investigation of disease outbreaks.",

keywords = "CONSUMPTION",

author = "Carrique-Mas, {Juan J.} and Tue, {Ngo T.} and Bryant, {Juliet E.} and Karen Saylors and Cuong, {Nguyen V.} and Hoa, {Ngo T.} and An, {Nguyen N.} and Hien, {Vo B.} and Lao, {Pham V.} and Tu, {Nguyen C.} and Chuyen, {Nguyen K.} and Chuc, {Nguyen T. K.} and Tan, {Dinh V.} and Duong, {Hoang Van V.} and Toan, {Tran K.} and Chi, {Nguyen T. Y.} and James Campbell and Rabaa, {Maia A.} and Behzad Nadjm and Mark Woolhouse and Heiman Wertheim and Guy Thwaites and Stephen Baker",

year = "2015",

month = dec,

day = "10",

doi = "10.1038/srep17965",

language = "English",

volume = "5",

journal = "Scientific Reports",

issn = "2045-2322",

publisher = "Nature Publishing Group",

}

Carrique-Mas, JJ, Tue, NT, Bryant, JE, Saylors, K, Cuong, NV, Hoa, NT, An, NN, Hien, VB, Lao, PV, Tu, NC, Chuyen, NK, Chuc, NTK, Tan, DV, Duong, HVV, Toan, TK, Chi, NTY, Campbell, J, Rabaa, MA, Nadjm, B, Woolhouse, M, Wertheim, H, Thwaites, G & Baker, S 2015, 'The baseline characteristics and interim analyses of the high-risk sentinel cohort of the Vietnam Initiative on Zoonotic InfectiONS (VIZIONS)', Scientific Reports, vol. 5, 17965. https://doi.org/10.1038/srep17965

TY - JOUR

T1 - The baseline characteristics and interim analyses of the high-risk sentinel cohort of the Vietnam Initiative on Zoonotic InfectiONS (VIZIONS)

AU - Carrique-Mas, Juan J.

AU - Tue, Ngo T.

AU - Bryant, Juliet E.

AU - Saylors, Karen

AU - Cuong, Nguyen V.

AU - Hoa, Ngo T.

AU - An, Nguyen N.

AU - Hien, Vo B.

AU - Lao, Pham V.

AU - Tu, Nguyen C.

AU - Chuyen, Nguyen K.

AU - Chuc, Nguyen T. K.

AU - Tan, Dinh V.

AU - Duong, Hoang Van V.

AU - Toan, Tran K.

AU - Chi, Nguyen T. Y.

AU - Campbell, James

AU - Rabaa, Maia A.

AU - Nadjm, Behzad

AU - Woolhouse, Mark

AU - Wertheim, Heiman

AU - Thwaites, Guy

AU - Baker, Stephen

PY - 2015/12/10

Y1 - 2015/12/10

N2 - The Vietnam Initiative for Zoonotic Infections (VIZIONS) includes community-based 'high-risk sentinel cohort' (HRSC) studies investigating individuals at risk of zoonotic infection due to occupational or residential exposure to animals. A total of 852 HRSC members were recruited between March 2013 and August 2014 from three provinces (Ha Noi, Dak Lak, and Dong Thap). The most numerous group (72.8%) corresponded to individuals living on farms, followed by slaughterers (16.3%) and animal health workers (8.5%). Nasal/pharyngeal and rectal swabs were collected from HRSC members at recruitment and after notifying illness. Exposure to exotic animals (including wild pigs, porcupine, monkey, civet, bamboo rat and bat) was highest for the Dak Lak cohort (53.7%), followed by Ha Noi (13.7%) and Dong Thap (4.0%). A total of 26.8% of individuals reported consumption of raw blood over the previous year; 33.6% slaughterers reported no use of protective equipment at work. Over 686 person-years of observation, 213 episodes of suspect infectious disease were notified, equivalent of 0.35 reports per person-year. Responsive samples were collected from animals in the farm cohort. There was noticeable time and space clustering of disease episodes suggesting that the VIZIONS set up is also suitable for the formal epidemiological investigation of disease outbreaks.

AB - The Vietnam Initiative for Zoonotic Infections (VIZIONS) includes community-based 'high-risk sentinel cohort' (HRSC) studies investigating individuals at risk of zoonotic infection due to occupational or residential exposure to animals. A total of 852 HRSC members were recruited between March 2013 and August 2014 from three provinces (Ha Noi, Dak Lak, and Dong Thap). The most numerous group (72.8%) corresponded to individuals living on farms, followed by slaughterers (16.3%) and animal health workers (8.5%). Nasal/pharyngeal and rectal swabs were collected from HRSC members at recruitment and after notifying illness. Exposure to exotic animals (including wild pigs, porcupine, monkey, civet, bamboo rat and bat) was highest for the Dak Lak cohort (53.7%), followed by Ha Noi (13.7%) and Dong Thap (4.0%). A total of 26.8% of individuals reported consumption of raw blood over the previous year; 33.6% slaughterers reported no use of protective equipment at work. Over 686 person-years of observation, 213 episodes of suspect infectious disease were notified, equivalent of 0.35 reports per person-year. Responsive samples were collected from animals in the farm cohort. There was noticeable time and space clustering of disease episodes suggesting that the VIZIONS set up is also suitable for the formal epidemiological investigation of disease outbreaks.

KW - CONSUMPTION

U2 - 10.1038/srep17965

DO - 10.1038/srep17965

M3 - Article

SN - 2045-2322

VL - 5

JO - Scientific Reports

JF - Scientific Reports

M1 - 17965

ER -

The baseline characteristics and interim analyses of the high-risk sentinel cohort of the Vietnam Initiative on Zoonotic InfectiONS (VIZIONS)

Abstract

Keywords / Materials (for Non-textual outputs)

Access to Document

Fingerprint

Cite this