The cholecystokinin type A receptor g.179A>G polymorphism affects feeding rate

R D Houston; K A Rance; E Sutcliffe; A L Archibald; C S Haley

doi:10.1111/j.1365-2052.2007.01692.x

The cholecystokinin type A receptor g.179A>G polymorphism affects feeding rate

R D Houston, K A Rance, E Sutcliffe, A L Archibald, C S Haley

Research output: Contribution to journal › Article › peer-review

Abstract

A polymorphism within the 5′ untranslated region of the cholecystokinin type A receptor (CCKAR) gene has been shown to affect feed intake and growth in commercial pig lines. To further investigate the phenotype of animals carrying alternative alleles at this polymorphism, we genotyped animals from a distinct segregating commercial line and an experimental cross F2 population, both with electronically recorded feeding pattern data. The data indicate that the daily feed intake increasing effect of the DQ496228:g.179G allele is mediated through a faster rate of feed intake, without evidence for an effect on other feeding behaviour traits.

Original language	English
Pages (from-to)	187-188
Number of pages	2
Journal	Animal Genetics
Volume	39
Issue number	2
DOIs	https://doi.org/10.1111/j.1365-2052.2007.01692.x
Publication status	Published - Apr 2008

Keywords

5' Untranslated Regions
Animals
Crosses, Genetic
Energy Intake
Feeding Behavior
Polymorphism, Genetic
Polymorphism, Single Nucleotide
Receptor, Cholecystokinin A
Satiety Response
Swine

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10.1111/j.1365-2052.2007.01692.x

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title = "The cholecystokinin type A receptor g.179A>G polymorphism affects feeding rate",

abstract = "A polymorphism within the 5′ untranslated region of the cholecystokinin type A receptor (CCKAR) gene has been shown to affect feed intake and growth in commercial pig lines. To further investigate the phenotype of animals carrying alternative alleles at this polymorphism, we genotyped animals from a distinct segregating commercial line and an experimental cross F2 population, both with electronically recorded feeding pattern data. The data indicate that the daily feed intake increasing effect of the DQ496228:g.179G allele is mediated through a faster rate of feed intake, without evidence for an effect on other feeding behaviour traits.",

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AU - Houston, R D

AU - Rance, K A

AU - Sutcliffe, E

AU - Archibald, A L

AU - Haley, C S

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AB - A polymorphism within the 5′ untranslated region of the cholecystokinin type A receptor (CCKAR) gene has been shown to affect feed intake and growth in commercial pig lines. To further investigate the phenotype of animals carrying alternative alleles at this polymorphism, we genotyped animals from a distinct segregating commercial line and an experimental cross F2 population, both with electronically recorded feeding pattern data. The data indicate that the daily feed intake increasing effect of the DQ496228:g.179G allele is mediated through a faster rate of feed intake, without evidence for an effect on other feeding behaviour traits.

KW - 5' Untranslated Regions

KW - Animals

KW - Crosses, Genetic

KW - Energy Intake

KW - Feeding Behavior

KW - Polymorphism, Genetic

KW - Polymorphism, Single Nucleotide

KW - Receptor, Cholecystokinin A

KW - Satiety Response

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The cholecystokinin type A receptor g.179A>G polymorphism affects feeding rate

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Keywords

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ISP1: Analysis and prediction in complex animal systems 2011-2012

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The cholecystokinin type A receptor g.179A>G polymorphism affects feeding rate

Abstract

Keywords

Access to Document

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Projects

ISP1: Analysis and prediction in complex animal systems 2011-2012

Cite this