The cholecystokinin type A receptor g.179A>G polymorphism affects feeding rate

R D Houston, K A Rance, E Sutcliffe, A L Archibald, C S Haley

Research output: Contribution to journalArticlepeer-review

Abstract

A polymorphism within the 5′ untranslated region of the cholecystokinin type A receptor (CCKAR) gene has been shown to affect feed intake and growth in commercial pig lines. To further investigate the phenotype of animals carrying alternative alleles at this polymorphism, we genotyped animals from a distinct segregating commercial line and an experimental cross F2 population, both with electronically recorded feeding pattern data. The data indicate that the daily feed intake increasing effect of the DQ496228:g.179G allele is mediated through a faster rate of feed intake, without evidence for an effect on other feeding behaviour traits.
Original languageEnglish
Pages (from-to)187-188
Number of pages2
JournalAnimal Genetics
Volume39
Issue number2
DOIs
Publication statusPublished - Apr 2008

Keywords

  • 5' Untranslated Regions
  • Animals
  • Crosses, Genetic
  • Energy Intake
  • Feeding Behavior
  • Polymorphism, Genetic
  • Polymorphism, Single Nucleotide
  • Receptor, Cholecystokinin A
  • Satiety Response
  • Swine

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