The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants

Ana Rio-machin; Tom Vulliamy; Nele Hug; Amanda Walne; Kiran Tawana; Shirleny Cardoso; Alicia Ellison; Nikolas Pontikos; Jun Wang; Hemanth Tummala; Ahad Fahad  Al Seraihi; Jenna Alnajar; Findlay Bewicke-Copley; Hannah Armes; Michael Barnett; Adrian Bloor; Csaba Bodor; David Bowen; Pierre Fenaux; Andrew Green; Andrew Hallahan; Henrik Hjorth-Hansen; Upal Hossain; Sally Killick; Sarah Lawson; Mark Layton; Alison M Male; Judith Marsh; Priyanka Mehta; Rogier Mous; Josep F Nomdedeu; Carolyn Owen; Jiri Pavlu; Elisabeth Payne; Rachel Protheroe; Claude Predhomme; Nuria Pujol-Moix; Aline Renneville; Nigel Russell; Anand Saggar; Gabriela Sciuccati; David Taussig; Cindy Toze; Anne Uyttebroeck; Peter Vandenberghe; Brigitte Schlegelberger; Tim Ripperger; Doris Steinemann; John Wu; Joanne Mason; Paula Page; Susanna  El Akiki; Kim Reay; Jamie D Cavenagh; Vincent Plagnol; Javier F. Caceres; Jude Fitzgibbon; Inderjeet Dokal

doi:10.1038/s41467-020-14829-5

The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants

Ana Rio-machin, Tom Vulliamy, Nele Hug, Amanda Walne, Kiran Tawana, Shirleny Cardoso, Alicia Ellison, Nikolas Pontikos, Jun Wang, Hemanth Tummala, Ahad Fahad Al Seraihi, Jenna Alnajar, Findlay Bewicke-Copley, Hannah Armes, Michael Barnett, Adrian Bloor, Csaba Bodor, David Bowen, Pierre Fenaux, Andrew GreenAndrew Hallahan, Henrik Hjorth-Hansen, Upal Hossain, Sally Killick, Sarah Lawson, Mark Layton, Alison M Male, Judith Marsh, Priyanka Mehta, Rogier Mous, Josep F Nomdedeu, Carolyn Owen, Jiri Pavlu, Elisabeth Payne, Rachel Protheroe, Claude Predhomme, Nuria Pujol-Moix, Aline Renneville, Nigel Russell, Anand Saggar, Gabriela Sciuccati, David Taussig, Cindy Toze, Anne Uyttebroeck, Peter Vandenberghe, Brigitte Schlegelberger, Tim Ripperger, Doris Steinemann, John Wu, Joanne Mason, Paula Page, Susanna El Akiki, Kim Reay, Jamie D Cavenagh, Vincent Plagnol, Javier F. Caceres, Jude Fitzgibbon, Inderjeet Dokal

Research output: Contribution to journal › Article › peer-review

Original language	English
Journal	Nature Communications
DOIs	https://doi.org/10.1038/s41467-020-14829-5
Publication status	Published - 25 Feb 2020

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Rio-machin, A., Vulliamy, T., Hug, N., Walne, A., Tawana, K., Cardoso, S., Ellison, A., Pontikos, N., Wang, J., Tummala, H., Al Seraihi, A. F., Alnajar, J., Bewicke-Copley, F., Armes, H., Barnett, M., Bloor, A., Bodor, C., Bowen, D., Fenaux, P., ... Dokal, I. (2020). The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants. Nature Communications. https://doi.org/10.1038/s41467-020-14829-5

Rio-machin, Ana ; Vulliamy, Tom ; Hug, Nele ; Walne, Amanda ; Tawana, Kiran ; Cardoso, Shirleny ; Ellison, Alicia ; Pontikos, Nikolas ; Wang, Jun ; Tummala, Hemanth ; Al Seraihi, Ahad Fahad ; Alnajar, Jenna ; Bewicke-Copley, Findlay ; Armes, Hannah ; Barnett, Michael ; Bloor, Adrian ; Bodor, Csaba ; Bowen, David ; Fenaux, Pierre ; Green, Andrew ; Hallahan, Andrew ; Hjorth-Hansen, Henrik ; Hossain, Upal ; Killick, Sally ; Lawson, Sarah ; Layton, Mark ; Male, Alison M ; Marsh, Judith ; Mehta, Priyanka ; Mous, Rogier ; Nomdedeu, Josep F ; Owen, Carolyn ; Pavlu, Jiri ; Payne, Elisabeth ; Protheroe, Rachel ; Predhomme, Claude ; Pujol-Moix, Nuria ; Renneville, Aline ; Russell, Nigel ; Saggar, Anand ; Sciuccati, Gabriela ; Taussig, David ; Toze, Cindy ; Uyttebroeck, Anne ; Vandenberghe, Peter ; Schlegelberger, Brigitte ; Ripperger, Tim ; Steinemann, Doris ; Wu, John ; Mason, Joanne ; Page, Paula ; El Akiki, Susanna ; Reay, Kim ; Cavenagh, Jamie D ; Plagnol, Vincent ; Caceres, Javier F. ; Fitzgibbon, Jude ; Dokal, Inderjeet. / The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants. In: Nature Communications. 2020.

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title = "The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants",

author = "Ana Rio-machin and Tom Vulliamy and Nele Hug and Amanda Walne and Kiran Tawana and Shirleny Cardoso and Alicia Ellison and Nikolas Pontikos and Jun Wang and Hemanth Tummala and {Al Seraihi}, {Ahad Fahad} and Jenna Alnajar and Findlay Bewicke-Copley and Hannah Armes and Michael Barnett and Adrian Bloor and Csaba Bodor and David Bowen and Pierre Fenaux and Andrew Green and Andrew Hallahan and Henrik Hjorth-Hansen and Upal Hossain and Sally Killick and Sarah Lawson and Mark Layton and Male, {Alison M} and Judith Marsh and Priyanka Mehta and Rogier Mous and Nomdedeu, {Josep F} and Carolyn Owen and Jiri Pavlu and Elisabeth Payne and Rachel Protheroe and Claude Predhomme and Nuria Pujol-Moix and Aline Renneville and Nigel Russell and Anand Saggar and Gabriela Sciuccati and David Taussig and Cindy Toze and Anne Uyttebroeck and Peter Vandenberghe and Brigitte Schlegelberger and Tim Ripperger and Doris Steinemann and John Wu and Joanne Mason and Paula Page and {El Akiki}, Susanna and Kim Reay and Cavenagh, {Jamie D} and Vincent Plagnol and Caceres, {Javier F.} and Jude Fitzgibbon and Inderjeet Dokal",

year = "2020",

month = feb,

day = "25",

doi = "10.1038/s41467-020-14829-5",

language = "English",

journal = "Nature Communications",

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Rio-machin, A, Vulliamy, T, Hug, N, Walne, A, Tawana, K, Cardoso, S, Ellison, A, Pontikos, N, Wang, J, Tummala, H, Al Seraihi, AF, Alnajar, J, Bewicke-Copley, F, Armes, H, Barnett, M, Bloor, A, Bodor, C, Bowen, D, Fenaux, P, Green, A, Hallahan, A, Hjorth-Hansen, H, Hossain, U, Killick, S, Lawson, S, Layton, M, Male, AM, Marsh, J, Mehta, P, Mous, R, Nomdedeu, JF, Owen, C, Pavlu, J, Payne, E, Protheroe, R, Predhomme, C, Pujol-Moix, N, Renneville, A, Russell, N, Saggar, A, Sciuccati, G, Taussig, D, Toze, C, Uyttebroeck, A, Vandenberghe, P, Schlegelberger, B, Ripperger, T, Steinemann, D, Wu, J, Mason, J, Page, P, El Akiki, S, Reay, K, Cavenagh, JD, Plagnol, V, Caceres, JF, Fitzgibbon, J & Dokal, I 2020, 'The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants', Nature Communications. https://doi.org/10.1038/s41467-020-14829-5

The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants. / Rio-machin, Ana; Vulliamy, Tom; Hug, Nele; Walne, Amanda; Tawana, Kiran; Cardoso, Shirleny; Ellison, Alicia; Pontikos, Nikolas; Wang, Jun; Tummala, Hemanth; Al Seraihi, Ahad Fahad ; Alnajar, Jenna; Bewicke-Copley, Findlay; Armes, Hannah; Barnett, Michael; Bloor, Adrian; Bodor, Csaba; Bowen, David; Fenaux, Pierre; Green, Andrew; Hallahan, Andrew; Hjorth-Hansen, Henrik; Hossain, Upal; Killick, Sally; Lawson, Sarah; Layton, Mark; Male, Alison M; Marsh, Judith; Mehta, Priyanka; Mous, Rogier; Nomdedeu, Josep F; Owen, Carolyn; Pavlu, Jiri; Payne, Elisabeth; Protheroe, Rachel; Predhomme, Claude; Pujol-Moix, Nuria; Renneville, Aline; Russell, Nigel; Saggar, Anand; Sciuccati, Gabriela; Taussig, David; Toze, Cindy; Uyttebroeck, Anne; Vandenberghe, Peter; Schlegelberger, Brigitte; Ripperger, Tim; Steinemann, Doris; Wu, John; Mason, Joanne; Page, Paula; El Akiki, Susanna ; Reay, Kim; Cavenagh, Jamie D; Plagnol, Vincent; Caceres, Javier F.; Fitzgibbon, Jude; Dokal, Inderjeet.

In: Nature Communications, 25.02.2020.

Research output: Contribution to journal › Article › peer-review

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AU - Vulliamy, Tom

AU - Hug, Nele

AU - Walne, Amanda

AU - Tawana, Kiran

AU - Cardoso, Shirleny

AU - Ellison, Alicia

AU - Pontikos, Nikolas

AU - Wang, Jun

AU - Tummala, Hemanth

AU - Al Seraihi, Ahad Fahad

AU - Alnajar, Jenna

AU - Bewicke-Copley, Findlay

AU - Armes, Hannah

AU - Barnett, Michael

AU - Bloor, Adrian

AU - Bodor, Csaba

AU - Bowen, David

AU - Fenaux, Pierre

AU - Green, Andrew

AU - Hallahan, Andrew

AU - Hjorth-Hansen, Henrik

AU - Hossain, Upal

AU - Killick, Sally

AU - Lawson, Sarah

AU - Layton, Mark

AU - Male, Alison M

AU - Marsh, Judith

AU - Mehta, Priyanka

AU - Mous, Rogier

AU - Nomdedeu, Josep F

AU - Owen, Carolyn

AU - Pavlu, Jiri

AU - Payne, Elisabeth

AU - Protheroe, Rachel

AU - Predhomme, Claude

AU - Pujol-Moix, Nuria

AU - Renneville, Aline

AU - Russell, Nigel

AU - Saggar, Anand

AU - Sciuccati, Gabriela

AU - Taussig, David

AU - Toze, Cindy

AU - Uyttebroeck, Anne

AU - Vandenberghe, Peter

AU - Schlegelberger, Brigitte

AU - Ripperger, Tim

AU - Steinemann, Doris

AU - Wu, John

AU - Mason, Joanne

AU - Page, Paula

AU - El Akiki, Susanna

AU - Reay, Kim

AU - Cavenagh, Jamie D

AU - Plagnol, Vincent

AU - Caceres, Javier F.

AU - Fitzgibbon, Jude

AU - Dokal, Inderjeet

PY - 2020/2/25

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DO - 10.1038/s41467-020-14829-5

M3 - Article

JO - Nature Communications

JF - Nature Communications

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