Abstract

CG-rich DNA "reader" proteins that bind non-methylated CpG sequences have emerged as critical factors to the process of cell differentiation and development. In a recent paper in Nature, Ko et al. show that the CXXC domain protein, IDAX, plays a crucial role as a CG-rich DNA-binding factor in the regulation of Ten-Eleven-Translocation 2 (TET2) protein function.
Original languageEnglish
Pages (from-to)973-4
Number of pages2
JournalCell Research
Volume23
Issue number8
DOIs
Publication statusPublished - Aug 2013

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