The Edinburgh City Hospital cohort: analysis of enrollment, progression and mortality by baseline covariates

R P Brettle; A J McNeil; S M Gore; A G Bird; C S Leen; A Richardson

The Edinburgh City Hospital cohort: analysis of enrollment, progression and mortality by baseline covariates

R P Brettle, A J McNeil, S M Gore, A G Bird, C S Leen, A Richardson

Research output: Contribution to journal › Article › peer-review

Abstract

We describe baseline characteristics, enrollment, progression and mortality of the Edinburgh City Hospital HIV cohort. There were 431 men and 191 (31%) women; 439 (71%) infected via injection drug use (IDU); 92 (15%) via homosexual intercourse; 84 (13%) via heterosexual intercourse and 7 from blood products. Median annual rate of CD4 cell loss was 49 (90% range: 15-146); Both homosexual men and patients aged > 40 years at enrollment lost CD4 cells significantly more quickly. In multifactorial analysis controlled for baseline CD4 count and IgA, there was no gender effect, but young patients (

Original language	English
Pages (from-to)	479-91
Number of pages	13
Journal	QJM: An International Journal of Medicine
Volume	88
Issue number	7
Publication status	Published - Jul 1995

Keywords

Acquired Immunodeficiency Syndrome
Adult
CD4 Lymphocyte Count
Cohort Studies
Disease Progression
Female
HIV Infections
Humans
Male
Prognosis
Scotland
Survival Rate

Cite this

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title = "The Edinburgh City Hospital cohort: analysis of enrollment, progression and mortality by baseline covariates",

abstract = "We describe baseline characteristics, enrollment, progression and mortality of the Edinburgh City Hospital HIV cohort. There were 431 men and 191 (31%) women; 439 (71%) infected via injection drug use (IDU); 92 (15%) via homosexual intercourse; 84 (13%) via heterosexual intercourse and 7 from blood products. Median annual rate of CD4 cell loss was 49 (90% range: 15-146); Both homosexual men and patients aged > 40 years at enrollment lost CD4 cells significantly more quickly. In multifactorial analysis controlled for baseline CD4 count and IgA, there was no gender effect, but young patients (",

keywords = "Acquired Immunodeficiency Syndrome, Adult, CD4 Lymphocyte Count, Cohort Studies, Disease Progression, Female, HIV Infections, Humans, Male, Prognosis, Scotland, Survival Rate",

author = "Brettle, {R P} and McNeil, {A J} and Gore, {S M} and Bird, {A G} and Leen, {C S} and A Richardson",

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T2 - analysis of enrollment, progression and mortality by baseline covariates

AU - Brettle, R P

AU - McNeil, A J

AU - Gore, S M

AU - Bird, A G

AU - Leen, C S

AU - Richardson, A

PY - 1995/7

Y1 - 1995/7

N2 - We describe baseline characteristics, enrollment, progression and mortality of the Edinburgh City Hospital HIV cohort. There were 431 men and 191 (31%) women; 439 (71%) infected via injection drug use (IDU); 92 (15%) via homosexual intercourse; 84 (13%) via heterosexual intercourse and 7 from blood products. Median annual rate of CD4 cell loss was 49 (90% range: 15-146); Both homosexual men and patients aged > 40 years at enrollment lost CD4 cells significantly more quickly. In multifactorial analysis controlled for baseline CD4 count and IgA, there was no gender effect, but young patients (

AB - We describe baseline characteristics, enrollment, progression and mortality of the Edinburgh City Hospital HIV cohort. There were 431 men and 191 (31%) women; 439 (71%) infected via injection drug use (IDU); 92 (15%) via homosexual intercourse; 84 (13%) via heterosexual intercourse and 7 from blood products. Median annual rate of CD4 cell loss was 49 (90% range: 15-146); Both homosexual men and patients aged > 40 years at enrollment lost CD4 cells significantly more quickly. In multifactorial analysis controlled for baseline CD4 count and IgA, there was no gender effect, but young patients (

KW - Acquired Immunodeficiency Syndrome

KW - Adult

KW - CD4 Lymphocyte Count

KW - Cohort Studies

KW - Disease Progression

KW - Female

KW - HIV Infections

KW - Humans

KW - Male

KW - Prognosis

KW - Scotland

KW - Survival Rate

M3 - Article

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VL - 88

SP - 479

EP - 491

JO - QJM: An International Journal of Medicine

JF - QJM: An International Journal of Medicine

SN - 1460-2725

IS - 7

ER -

The Edinburgh City Hospital cohort: analysis of enrollment, progression and mortality by baseline covariates

Abstract

Keywords

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