The effect of kyphoscoliosis on intervertebral disc degeneration in dogs

Kiterie Faller, Jacques Penderis, Catherine Stalin, Julien Guevar, Carmen Yeamans, Rodrigo Gutierrez-Quintana

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

In people, abnormalities in vertebral column conformation, such as kyphoscoliosis, induce degenerative changes in adjacent intervertebral disc (IVD) structure and composition. It was hypothesised that canine IVDs adjacent to a vertebral malformation undergo early degeneration. In a blinded retrospective study, thoracic IVD degeneration was evaluated in 14 dogs on magnetic resonance images using Pfirrmann's grade. IVDs adjacent to a vertebral malformation had higher grades of degeneration than non-adjacent IVDs (P < 0.0001). There was an age-dependency, with dogs between 1 and 4 years showing higher grade of degeneration in adjacent than non-adjacent IVDs (P < 0.0001). Conversely, in older dogs, all IVDs - including the non-adjacents - showed degenerative signs, possibly due to normal aging. These results suggest that congenital vertebral malformation results in early degeneration of adjacent IVDs.

Original languageEnglish
Pages (from-to)449-51
Number of pages3
JournalVeterinary Journal
Issue number3
Early online date31 Mar 2014
Publication statusPublished - Jun 2014

Keywords / Materials (for Non-textual outputs)

  • Age Factors
  • Animals
  • Dog Diseases
  • Dogs
  • Female
  • Intervertebral Disc
  • Intervertebral Disc Degeneration
  • Kyphosis
  • Magnetic Resonance Imaging
  • Male
  • Retrospective Studies
  • Scoliosis
  • Thoracic Vertebrae
  • Journal Article


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