The effect of peripherally inserted central catheter (PICC) valve technology on catheter occlusion rates--the 'ELeCTRiC' study

Andrew J Johnston; Carmel T Streater; Remy Noorani; Joanne L Crofts; Aldwin B Del Mundo; Richard A Parker

doi:10.5301/jva.5000071

The effect of peripherally inserted central catheter (PICC) valve technology on catheter occlusion rates--the 'ELeCTRiC' study

Andrew J Johnston, Carmel T Streater, Remy Noorani, Joanne L Crofts, Aldwin B Del Mundo, Richard A Parker

Research output: Contribution to journal › Article › peer-review

Abstract

PURPOSE: Peripherally Inserted Central Catheters (PICCs) are increasingly being used to provide short to medium-term central venous access. The current study was designed to test the hypothesis that PICC valve technology does not influence PICC occlusion rates.

METHODS: Intensive care unit (ICU) patients who required a PICC were randomized to one of three types of dual lumen PICC (open ended non-valved, Groshong valve, PASV valve). PICC occlusions were recorded and managed with a protocol that used urokinase.

RESULTS: A total of 102 patients were recruited to the study. The overall risk of occlusion per catheter was 35% (95% CI 26% to 44%). The overall rate of occlusion was 76 occlusions per 1000 catheter days (95% CI 61 to 95). Presence or type of valve did not significantly influence this rate (open-ended non-valved PICC 38% of catheters, 79 occlusions per 1000 catheter days; Groshong 38% of catheters, 60 occlusions per 1000 catheter days; PASV 27% of catheters, 99 occlusions per 1000 catheter days). The dose of urokinase required to treat PICC occlusions did not significantly differ between PICC types.

CONCLUSIONS: Valved PICCs do not appear to influence PICC occlusion rates.

Original language	English
Pages (from-to)	421-5
Number of pages	5
Journal	The Journal of Vascular Access (JVA)
Volume	13
Issue number	4
DOIs	https://doi.org/10.5301/jva.5000071
Publication status	Published - 4 Feb 2012

Keywords / Materials (for Non-textual outputs)

Adult
Aged
Catheter Obstruction
Catheterization, Central Venous
Catheterization, Peripheral
Central Venous Catheters
Early Termination of Clinical Trials
England
Equipment Design
Female
Fibrinolytic Agents
Humans
Intensive Care Units
Male
Middle Aged
Risk Factors
Thrombolytic Therapy
Treatment Outcome
Upper Extremity Deep Vein Thrombosis
Urokinase-Type Plasminogen Activator

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10.5301/jva.5000071

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@article{bc31f24af3294446b8322989850e0d8f,

title = "The effect of peripherally inserted central catheter (PICC) valve technology on catheter occlusion rates--the 'ELeCTRiC' study",

abstract = "PURPOSE: Peripherally Inserted Central Catheters (PICCs) are increasingly being used to provide short to medium-term central venous access. The current study was designed to test the hypothesis that PICC valve technology does not influence PICC occlusion rates.METHODS: Intensive care unit (ICU) patients who required a PICC were randomized to one of three types of dual lumen PICC (open ended non-valved, Groshong valve, PASV valve). PICC occlusions were recorded and managed with a protocol that used urokinase.RESULTS: A total of 102 patients were recruited to the study. The overall risk of occlusion per catheter was 35\% (95\% CI 26\% to 44\%). The overall rate of occlusion was 76 occlusions per 1000 catheter days (95\% CI 61 to 95). Presence or type of valve did not significantly influence this rate (open-ended non-valved PICC 38\% of catheters, 79 occlusions per 1000 catheter days; Groshong 38\% of catheters, 60 occlusions per 1000 catheter days; PASV 27\% of catheters, 99 occlusions per 1000 catheter days). The dose of urokinase required to treat PICC occlusions did not significantly differ between PICC types.CONCLUSIONS: Valved PICCs do not appear to influence PICC occlusion rates.",

keywords = "Adult, Aged, Catheter Obstruction, Catheterization, Central Venous, Catheterization, Peripheral, Central Venous Catheters, Early Termination of Clinical Trials, England, Equipment Design, Female, Fibrinolytic Agents, Humans, Intensive Care Units, Male, Middle Aged, Risk Factors, Thrombolytic Therapy, Treatment Outcome, Upper Extremity Deep Vein Thrombosis, Urokinase-Type Plasminogen Activator",

author = "Johnston, \{Andrew J\} and Streater, \{Carmel T\} and Remy Noorani and Crofts, \{Joanne L\} and \{Del Mundo\}, \{Aldwin B\} and Parker, \{Richard A\}",

year = "2012",

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doi = "10.5301/jva.5000071",

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T1 - The effect of peripherally inserted central catheter (PICC) valve technology on catheter occlusion rates--the 'ELeCTRiC' study

AU - Johnston, Andrew J

AU - Streater, Carmel T

AU - Noorani, Remy

AU - Crofts, Joanne L

AU - Del Mundo, Aldwin B

AU - Parker, Richard A

PY - 2012/2/4

Y1 - 2012/2/4

N2 - PURPOSE: Peripherally Inserted Central Catheters (PICCs) are increasingly being used to provide short to medium-term central venous access. The current study was designed to test the hypothesis that PICC valve technology does not influence PICC occlusion rates.METHODS: Intensive care unit (ICU) patients who required a PICC were randomized to one of three types of dual lumen PICC (open ended non-valved, Groshong valve, PASV valve). PICC occlusions were recorded and managed with a protocol that used urokinase.RESULTS: A total of 102 patients were recruited to the study. The overall risk of occlusion per catheter was 35% (95% CI 26% to 44%). The overall rate of occlusion was 76 occlusions per 1000 catheter days (95% CI 61 to 95). Presence or type of valve did not significantly influence this rate (open-ended non-valved PICC 38% of catheters, 79 occlusions per 1000 catheter days; Groshong 38% of catheters, 60 occlusions per 1000 catheter days; PASV 27% of catheters, 99 occlusions per 1000 catheter days). The dose of urokinase required to treat PICC occlusions did not significantly differ between PICC types.CONCLUSIONS: Valved PICCs do not appear to influence PICC occlusion rates.

AB - PURPOSE: Peripherally Inserted Central Catheters (PICCs) are increasingly being used to provide short to medium-term central venous access. The current study was designed to test the hypothesis that PICC valve technology does not influence PICC occlusion rates.METHODS: Intensive care unit (ICU) patients who required a PICC were randomized to one of three types of dual lumen PICC (open ended non-valved, Groshong valve, PASV valve). PICC occlusions were recorded and managed with a protocol that used urokinase.RESULTS: A total of 102 patients were recruited to the study. The overall risk of occlusion per catheter was 35% (95% CI 26% to 44%). The overall rate of occlusion was 76 occlusions per 1000 catheter days (95% CI 61 to 95). Presence or type of valve did not significantly influence this rate (open-ended non-valved PICC 38% of catheters, 79 occlusions per 1000 catheter days; Groshong 38% of catheters, 60 occlusions per 1000 catheter days; PASV 27% of catheters, 99 occlusions per 1000 catheter days). The dose of urokinase required to treat PICC occlusions did not significantly differ between PICC types.CONCLUSIONS: Valved PICCs do not appear to influence PICC occlusion rates.

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KW - Early Termination of Clinical Trials

KW - England

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KW - Female

KW - Fibrinolytic Agents

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KW - Intensive Care Units

KW - Male

KW - Middle Aged

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KW - Treatment Outcome

KW - Upper Extremity Deep Vein Thrombosis

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ER -

The effect of peripherally inserted central catheter (PICC) valve technology on catheter occlusion rates--the 'ELeCTRiC' study

Abstract

Keywords / Materials (for Non-textual outputs)

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