The effect of ultraviolet (UV) A1, UVB and solar-simulated radiation on p53 activation and p21

P E Beattie; L E Finlan; N M Kernohan; G Thomson; T R Hupp; S H Ibbotson

doi:10.1111/j.1365-2133.2005.06557.x

The effect of ultraviolet (UV) A1, UVB and solar-simulated radiation on p53 activation and p21

P E Beattie, L E Finlan, N M Kernohan, G Thomson, T R Hupp, S H Ibbotson

Research output: Contribution to journal › Article › peer-review

Abstract

High-dose ultraviolet (UV) A1 therapy (doses in the order of 130 J cm(-2)) is effective for atopic dermatitis and scleroderma. UVA1 has been shown to induce a dose-dependent increase in p53 expression in keratinocytes.

Original language	English
Pages (from-to)	1001-8
Number of pages	8
Journal	British journal of dermatology
Volume	152
Issue number	5
DOIs	https://doi.org/10.1111/j.1365-2133.2005.06557.x
Publication status	Published - May 2005

Keywords / Materials (for Non-textual outputs)

Adult
Apoptosis
Cell Cycle Proteins
Cyclin-Dependent Kinase Inhibitor p21
Erythema
Humans
Middle Aged
Phosphorylation
Radiation Dosage
Radiation Injuries
Skin
Sunlight
Tumor Suppressor Protein p53
Ultraviolet Rays

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10.1111/j.1365-2133.2005.06557.x

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title = "The effect of ultraviolet (UV) A1, UVB and solar-simulated radiation on p53 activation and p21",

abstract = "High-dose ultraviolet (UV) A1 therapy (doses in the order of 130 J cm(-2)) is effective for atopic dermatitis and scleroderma. UVA1 has been shown to induce a dose-dependent increase in p53 expression in keratinocytes.",

keywords = "Adult, Apoptosis, Cell Cycle Proteins, Cyclin-Dependent Kinase Inhibitor p21, Erythema, Humans, Middle Aged, Phosphorylation, Radiation Dosage, Radiation Injuries, Skin, Sunlight, Tumor Suppressor Protein p53, Ultraviolet Rays",

author = "Beattie, {P E} and Finlan, {L E} and Kernohan, {N M} and G Thomson and Hupp, {T R} and Ibbotson, {S H}",

year = "2005",

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AU - Beattie, P E

AU - Finlan, L E

AU - Kernohan, N M

AU - Thomson, G

AU - Hupp, T R

AU - Ibbotson, S H

PY - 2005/5

Y1 - 2005/5

N2 - High-dose ultraviolet (UV) A1 therapy (doses in the order of 130 J cm(-2)) is effective for atopic dermatitis and scleroderma. UVA1 has been shown to induce a dose-dependent increase in p53 expression in keratinocytes.

AB - High-dose ultraviolet (UV) A1 therapy (doses in the order of 130 J cm(-2)) is effective for atopic dermatitis and scleroderma. UVA1 has been shown to induce a dose-dependent increase in p53 expression in keratinocytes.

KW - Adult

KW - Apoptosis

KW - Cell Cycle Proteins

KW - Cyclin-Dependent Kinase Inhibitor p21

KW - Erythema

KW - Humans

KW - Middle Aged

KW - Phosphorylation

KW - Radiation Dosage

KW - Radiation Injuries

KW - Skin

KW - Sunlight

KW - Tumor Suppressor Protein p53

KW - Ultraviolet Rays

U2 - 10.1111/j.1365-2133.2005.06557.x

DO - 10.1111/j.1365-2133.2005.06557.x

M3 - Article

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SN - 0007-0963

VL - 152

SP - 1001

EP - 1008

JO - British journal of dermatology

JF - British journal of dermatology

IS - 5

ER -

The effect of ultraviolet (UV) A1, UVB and solar-simulated radiation on p53 activation and p21

Abstract

Keywords / Materials (for Non-textual outputs)

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