The effectiveness of a targeted re-treatment programme in reducing the prevalence of trypanosomiasis in cattle in Uganda

Louise Hamill, Richard Selby, Christine Amongi Acup, Beatrix von Wissmann, Kim Picozzi, Susan Welburn

Research output: Contribution to conferenceOther

Abstract

The “Stamp Out Sleeping Sickness (SOS)” programme was launched in 2006, and aims to halt northward spread of Trypanosoma brucei rhodesiense in Uganda by mass trypanocidal treatment of the cattle reservoir. Phase 1 targeted the most northerly of the newly affected districts. Post-treatment monitoring revealed a cluster of villages in which T. b. rhodesiense remained present in the cattle reservoir. The villages were located close to one another and within parishes that continued to report human sleeping sickness cases, indicating transmission may not have been properly interrupted. Subsequently, re-treatment of this high risk area was undertaken.

This work assesses the impact of the SOS re-treatment intervention on the prevalence of T. vivax, T. b. brucei and T. b. rhodesiense by analyzing cattle blood samples from 20 villages within the re-treatment area. Samples were taken immediately before and six months after re-treatment. Samples were then subjected to PCR based methods for the detection of parasite DNA.

The results of this analysis show the re-treatment programme was successful in reducing the overall prevalence of trypanosomiasis in the targeted area. A significant drop in trypanosome prevalence was observed between the baseline and six month samples, both overall and in each individual species detected.

Original languageEnglish
Publication statusPublished - 2010
EventBritish Society for Parasitology Spring Meeting 2010 - Cardiff, United Kingdom
Duration: 5 Apr 20108 Apr 2010

Conference

ConferenceBritish Society for Parasitology Spring Meeting 2010
CountryUnited Kingdom
CityCardiff
Period5/04/108/04/10

Fingerprint

Dive into the research topics of 'The effectiveness of a targeted re-treatment programme in reducing the prevalence of trypanosomiasis in cattle in Uganda'. Together they form a unique fingerprint.

Cite this