The “Stamp Out Sleeping Sickness (SOS)” programme was launched in 2006, and aims to halt northward spread of Trypanosoma brucei rhodesiense in Uganda by mass trypanocidal treatment of the cattle reservoir. Phase 1 targeted the most northerly of the newly affected districts. Post-treatment monitoring revealed a cluster of villages in which T. b. rhodesiense remained present in the cattle reservoir. The villages were located close to one another and within parishes that continued to report human sleeping sickness cases, indicating transmission may not have been properly interrupted. Subsequently, re-treatment of this high risk area was undertaken.
This work assesses the impact of the SOS re-treatment intervention on the prevalence of T. vivax, T. b. brucei and T. b. rhodesiense by analyzing cattle blood samples from 20 villages within the re-treatment area. Samples were taken immediately before and six months after re-treatment. Samples were then subjected to PCR based methods for the detection of parasite DNA.
The results of this analysis show the re-treatment programme was successful in reducing the overall prevalence of trypanosomiasis in the targeted area. A significant drop in trypanosome prevalence was observed between the baseline and six month samples, both overall and in each individual species detected.
|Publication status||Published - 2010|
|Event||British Society for Parasitology Spring Meeting 2010 - Cardiff, United Kingdom|
Duration: 5 Apr 2010 → 8 Apr 2010
|Conference||British Society for Parasitology Spring Meeting 2010|
|Period||5/04/10 → 8/04/10|