The effects of selection indices for sustainable hill sheep production on carcass composition and muscularity of lambs using X-ray tomography.

N. R. Lambe, L. Bünger, S. C. Bishop, Geoff Simm, J. Conington

Research output: Contribution to journalArticlepeer-review

Abstract

The nonsense-mediated mRNA decay (NMD) pathway is a surveillance mechanism that targets the degradation of mRNAs harboring premature termination codons (PTCs). Two key aspects of NMD are the definition of a PTC codon and the identification of the molecular machinery dedicated to this mechanism. This chapter describes the development of transgenic reporters as well as the use of genome-wide RNAi and genetic screens to identify novel components of the NMD pathway in the nematode Caenorhabditis elegans
Original languageEnglish
Pages (from-to)27-35
Number of pages9
JournalAnimal Genetics
Volume2
Publication statusPublished - 2008

Keywords / Materials (for Non-textual outputs)

  • Caenorhabditis elegans
  • Codon
  • development
  • genetics
  • human
  • Research
  • Research Support
  • RNAi
  • Scotland
  • Transgenic

Fingerprint

Dive into the research topics of 'The effects of selection indices for sustainable hill sheep production on carcass composition and muscularity of lambs using X-ray tomography.'. Together they form a unique fingerprint.

Cite this