The emergence of mecC methicillin-resistant Staphylococcus aureus

Gavin K Paterson, Ewan M Harrison, Mark A Holmes

Research output: Contribution to journalArticlepeer-review

Abstract

The report of methicillin-resistant Staphylococcus aureus (MRSA) encoding a divergent mecA gene in 2011 was highly significant. This homologue, designated mecC, poses diagnostic problems with the potential to be misdiagnosed as methicillin-sensitive S. aureus, with important potential consequences for individual patients and for the surveillance of MRSA. mecC MRSA have now been reported from 13 European countries and have been isolated from 14 different host species, with evidence of a recent increase in Denmark. The emergence of mecC MRSA is a topic of interest to human and veterinary microbiology, and we consider it timely to review here its discovery and subsequent investigation.

Original languageEnglish
Pages (from-to)42-7
Number of pages6
JournalTrends in Microbiology
Volume22
Issue number1
DOIs
Publication statusPublished - Jan 2014

Keywords

  • Animals
  • Diagnostic Errors
  • Europe
  • Genes, Bacterial
  • Humans
  • Methicillin-Resistant Staphylococcus aureus
  • Microbial Sensitivity Tests
  • Staphylococcal Infections
  • Journal Article
  • Research Support, Non-U.S. Gov't
  • Review

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