The ethics of gene therapy

Sarah Chan*, John Harris

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Recent developments have progressed in areas of science that pertain to gene therapy and its ethical implications. This review discusses the current state of therapeutic gene technologies, including stem cell therapies and genetic modification, and identifies ethical issues of concern in relation to the science of gene therapy and its application, including the ethics of embryonic stem cell research and therapeutic cloning, the risks associated with gene therapy, and the ethics of clinical research in developing new therapeutic technologies. Additionally, ethical issues relating to genetic modification itself are considered: the significance of the human genome, the distinction between therapy and enhancement, and concerns regarding gene therapy as a eugenic practice.

Original languageEnglish
Pages (from-to)377-383
Number of pages7
JournalCurrent opinion in molecular therapeutics
Volume8
Issue number5
Publication statusPublished - Oct 2006

Keywords

  • embryo research
  • enhancement
  • ethics
  • gene therapy
  • genetic modification
  • stem cells
  • EMBRYONIC STEM-CELLS
  • HUMAN LIFE-SPAN
  • JAN 20 2006
  • REPRODUCTIVE TECHNOLOGIES
  • NATURAL REPRODUCTION
  • HUMAN BLASTOCYSTS
  • NUCLEAR TRANSFER
  • VALUE ARGUMENT
  • RETRACTED SEE
  • PG 335

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