The European Sleep Apnoea Database (ESADA): report from 22 European sleep laboratories

J. Hedner; L. Grote; M. Bonsignore; W. McNicholas; P. Lavie; G. Parati; P. Sliwinski; F. Barbe; W. De Backer; P. Escourrou; I. Fietze; J. A. Kvamme; C. Lombardi; O. Marrone; J. F. Masa; J. M. Montserrat; T. Penzel; M. Pretl; R. Riha; D. Rodenstein; T. Saaresranta; R. Schulz; R. Tkacova; G. Varoneckas; A. Vitols; H. Vrints; J. Zielinski

doi:10.1183/09031936.00046710

The European Sleep Apnoea Database (ESADA): report from 22 European sleep laboratories

J. Hedner, L. Grote^*, M. Bonsignore, W. McNicholas, P. Lavie, G. Parati, P. Sliwinski, F. Barbe, W. De Backer, P. Escourrou, I. Fietze, J. A. Kvamme, C. Lombardi, O. Marrone, J. F. Masa, J. M. Montserrat, T. Penzel, M. Pretl, R. Riha, D. RodensteinT. Saaresranta, R. Schulz, R. Tkacova, G. Varoneckas, A. Vitols, H. Vrints, J. Zielinski

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

The European Sleep Apnoea Database (ESADA) reflects a network of 22 sleep disorder centres in Europe enabled by a COST action B26 programme. This ongoing project aims to describe differences in standard clinical care of patients with obstructive sleep apnoea (OSA) and to establish a resource for genetic research in this disorder.

Patients with suspected OSA are consecutively included and followed up according to local clinical standards. Anthropometrics, medical history, medication, daytime symptoms and sleep data (poly-somnography or cardiorespiratory polygraphy) are recorded in a structured web-based report form.

5,103 patients (1,426 females, mean +/- SD age 51.8 +/- 12.6 yrs, 79.4% with apnoea/hypopnoea index (AHI) >= 5 events.h(-1)) were included from March 15, 2007 to August 1, 2009. Morbid obesity (body mass index >= 35 kg.m(-2)) was present in 21.1% of males and 28.6% of females. Cardiovascular, metabolic and pulmonary comorbidities were frequent (49.1%, 32.9% and 14.2%, respectively). Patients investigated with a polygraphic method had a lower AHI than those undergoing polysomnography (23.2 +/- 23.5 versus 29.1 +/- 26.3 events.h(-1), p <0.0001).

The ESADA is a rapidly growing multicentre patient cohort that enables unique outcome research opportunities and genotyping. The first cross-sectional analysis reveals a high prevalence of cardiovascular and metabolic morbidity in patients investigated for OSA.

Original language	English
Pages (from-to)	635-642
Number of pages	8
Journal	European Respiratory Journal
Volume	38
Issue number	3
DOIs	https://doi.org/10.1183/09031936.00046710
Publication status	Published - Sept 2011

Keywords / Materials (for Non-textual outputs)

Comorbidity
European Sleep Apnoea Database
genetic
multicentre cohort
obstructive sleep apnoea syndrome
CARDIOVASCULAR-DISEASE
RISK-FACTOR
EPIDEMIOLOGY
HYPERTENSION
PERSPECTIVE

Access to Document

10.1183/09031936.00046710

Cite this

Hedner, J., Grote, L., Bonsignore, M., McNicholas, W., Lavie, P., Parati, G., Sliwinski, P., Barbe, F., De Backer, W., Escourrou, P., Fietze, I., Kvamme, J. A., Lombardi, C., Marrone, O., Masa, J. F., Montserrat, J. M., Penzel, T., Pretl, M., Riha, R., ... Zielinski, J. (2011). The European Sleep Apnoea Database (ESADA): report from 22 European sleep laboratories. European Respiratory Journal, 38(3), 635-642. https://doi.org/10.1183/09031936.00046710

@article{d78e529534904d2590b3759e7d219eb0,

title = "The European Sleep Apnoea Database (ESADA): report from 22 European sleep laboratories",

abstract = "The European Sleep Apnoea Database (ESADA) reflects a network of 22 sleep disorder centres in Europe enabled by a COST action B26 programme. This ongoing project aims to describe differences in standard clinical care of patients with obstructive sleep apnoea (OSA) and to establish a resource for genetic research in this disorder.Patients with suspected OSA are consecutively included and followed up according to local clinical standards. Anthropometrics, medical history, medication, daytime symptoms and sleep data (poly-somnography or cardiorespiratory polygraphy) are recorded in a structured web-based report form.5,103 patients (1,426 females, mean +/- SD age 51.8 +/- 12.6 yrs, 79.4% with apnoea/hypopnoea index (AHI) >= 5 events.h(-1)) were included from March 15, 2007 to August 1, 2009. Morbid obesity (body mass index >= 35 kg.m(-2)) was present in 21.1% of males and 28.6% of females. Cardiovascular, metabolic and pulmonary comorbidities were frequent (49.1%, 32.9% and 14.2%, respectively). Patients investigated with a polygraphic method had a lower AHI than those undergoing polysomnography (23.2 +/- 23.5 versus 29.1 +/- 26.3 events.h(-1), p <0.0001).The ESADA is a rapidly growing multicentre patient cohort that enables unique outcome research opportunities and genotyping. The first cross-sectional analysis reveals a high prevalence of cardiovascular and metabolic morbidity in patients investigated for OSA.",

keywords = "Comorbidity, European Sleep Apnoea Database, genetic, multicentre cohort, obstructive sleep apnoea syndrome, CARDIOVASCULAR-DISEASE, RISK-FACTOR, EPIDEMIOLOGY, HYPERTENSION, PERSPECTIVE",

author = "J. Hedner and L. Grote and M. Bonsignore and W. McNicholas and P. Lavie and G. Parati and P. Sliwinski and F. Barbe and {De Backer}, W. and P. Escourrou and I. Fietze and Kvamme, {J. A.} and C. Lombardi and O. Marrone and Masa, {J. F.} and Montserrat, {J. M.} and T. Penzel and M. Pretl and R. Riha and D. Rodenstein and T. Saaresranta and R. Schulz and R. Tkacova and G. Varoneckas and A. Vitols and H. Vrints and J. Zielinski",

year = "2011",

month = sep,

doi = "10.1183/09031936.00046710",

language = "English",

volume = "38",

pages = "635--642",

journal = "European Respiratory Journal",

issn = "0903-1936",

publisher = "European Respiratory Society",

number = "3",

}

Hedner, J, Grote, L, Bonsignore, M, McNicholas, W, Lavie, P, Parati, G, Sliwinski, P, Barbe, F, De Backer, W, Escourrou, P, Fietze, I, Kvamme, JA, Lombardi, C, Marrone, O, Masa, JF, Montserrat, JM, Penzel, T, Pretl, M, Riha, R, Rodenstein, D, Saaresranta, T, Schulz, R, Tkacova, R, Varoneckas, G, Vitols, A, Vrints, H & Zielinski, J 2011, 'The European Sleep Apnoea Database (ESADA): report from 22 European sleep laboratories', European Respiratory Journal, vol. 38, no. 3, pp. 635-642. https://doi.org/10.1183/09031936.00046710

TY - JOUR

T1 - The European Sleep Apnoea Database (ESADA)

T2 - report from 22 European sleep laboratories

AU - Hedner, J.

AU - Grote, L.

AU - Bonsignore, M.

AU - McNicholas, W.

AU - Lavie, P.

AU - Parati, G.

AU - Sliwinski, P.

AU - Barbe, F.

AU - De Backer, W.

AU - Escourrou, P.

AU - Fietze, I.

AU - Kvamme, J. A.

AU - Lombardi, C.

AU - Marrone, O.

AU - Masa, J. F.

AU - Montserrat, J. M.

AU - Penzel, T.

AU - Pretl, M.

AU - Riha, R.

AU - Rodenstein, D.

AU - Saaresranta, T.

AU - Schulz, R.

AU - Tkacova, R.

AU - Varoneckas, G.

AU - Vitols, A.

AU - Vrints, H.

AU - Zielinski, J.

PY - 2011/9

Y1 - 2011/9

N2 - The European Sleep Apnoea Database (ESADA) reflects a network of 22 sleep disorder centres in Europe enabled by a COST action B26 programme. This ongoing project aims to describe differences in standard clinical care of patients with obstructive sleep apnoea (OSA) and to establish a resource for genetic research in this disorder.Patients with suspected OSA are consecutively included and followed up according to local clinical standards. Anthropometrics, medical history, medication, daytime symptoms and sleep data (poly-somnography or cardiorespiratory polygraphy) are recorded in a structured web-based report form.5,103 patients (1,426 females, mean +/- SD age 51.8 +/- 12.6 yrs, 79.4% with apnoea/hypopnoea index (AHI) >= 5 events.h(-1)) were included from March 15, 2007 to August 1, 2009. Morbid obesity (body mass index >= 35 kg.m(-2)) was present in 21.1% of males and 28.6% of females. Cardiovascular, metabolic and pulmonary comorbidities were frequent (49.1%, 32.9% and 14.2%, respectively). Patients investigated with a polygraphic method had a lower AHI than those undergoing polysomnography (23.2 +/- 23.5 versus 29.1 +/- 26.3 events.h(-1), p <0.0001).The ESADA is a rapidly growing multicentre patient cohort that enables unique outcome research opportunities and genotyping. The first cross-sectional analysis reveals a high prevalence of cardiovascular and metabolic morbidity in patients investigated for OSA.

AB - The European Sleep Apnoea Database (ESADA) reflects a network of 22 sleep disorder centres in Europe enabled by a COST action B26 programme. This ongoing project aims to describe differences in standard clinical care of patients with obstructive sleep apnoea (OSA) and to establish a resource for genetic research in this disorder.Patients with suspected OSA are consecutively included and followed up according to local clinical standards. Anthropometrics, medical history, medication, daytime symptoms and sleep data (poly-somnography or cardiorespiratory polygraphy) are recorded in a structured web-based report form.5,103 patients (1,426 females, mean +/- SD age 51.8 +/- 12.6 yrs, 79.4% with apnoea/hypopnoea index (AHI) >= 5 events.h(-1)) were included from March 15, 2007 to August 1, 2009. Morbid obesity (body mass index >= 35 kg.m(-2)) was present in 21.1% of males and 28.6% of females. Cardiovascular, metabolic and pulmonary comorbidities were frequent (49.1%, 32.9% and 14.2%, respectively). Patients investigated with a polygraphic method had a lower AHI than those undergoing polysomnography (23.2 +/- 23.5 versus 29.1 +/- 26.3 events.h(-1), p <0.0001).The ESADA is a rapidly growing multicentre patient cohort that enables unique outcome research opportunities and genotyping. The first cross-sectional analysis reveals a high prevalence of cardiovascular and metabolic morbidity in patients investigated for OSA.

KW - Comorbidity

KW - European Sleep Apnoea Database

KW - genetic

KW - multicentre cohort

KW - obstructive sleep apnoea syndrome

KW - CARDIOVASCULAR-DISEASE

KW - RISK-FACTOR

KW - EPIDEMIOLOGY

KW - HYPERTENSION

KW - PERSPECTIVE

U2 - 10.1183/09031936.00046710

DO - 10.1183/09031936.00046710

M3 - Article

SN - 0903-1936

VL - 38

SP - 635

EP - 642

JO - European Respiratory Journal

JF - European Respiratory Journal

IS - 3

ER -

The European Sleep Apnoea Database (ESADA): report from 22 European sleep laboratories

Abstract

Keywords / Materials (for Non-textual outputs)

Access to Document

Fingerprint

Cite this