The fat controller: roles of palmitoylation in intracellular protein trafficking and targeting to membrane microdomains (Review)

Jennifer Greaves; Gerald R. Prescott; Oforiwa A. Gorleku; Luke H. Chamberlain

doi:10.1080/09687680802620351

The fat controller: roles of palmitoylation in intracellular protein trafficking and targeting to membrane microdomains (Review)

Jennifer Greaves, Gerald R. Prescott, Oforiwa A. Gorleku, Luke H. Chamberlain

Deanery of Biomedical Sciences

Research output: Contribution to journal › Literature review › peer-review

Abstract / Description of output

The attachment of palmitic acid to the amino acid cysteine via thioester linkage (S-palmitoylation) is a common post-translational modification of eukaryotic proteins. In this review, we discuss the role of palmitoylation as a versatile protein sorting signal, regulating protein trafficking between distinct intracellular compartments and the micro-localization of proteins within membranes.

Original language	English
Pages (from-to)	67-79
Number of pages	13
Journal	Molecular Membrane Biology
Volume	26
Issue number	1-2
DOIs	https://doi.org/10.1080/09687680802620351
Publication status	Published - 2009

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10.1080/09687680802620351

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abstract = "The attachment of palmitic acid to the amino acid cysteine via thioester linkage (S-palmitoylation) is a common post-translational modification of eukaryotic proteins. In this review, we discuss the role of palmitoylation as a versatile protein sorting signal, regulating protein trafficking between distinct intracellular compartments and the micro-localization of proteins within membranes.",

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AU - Chamberlain, Luke H.

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AB - The attachment of palmitic acid to the amino acid cysteine via thioester linkage (S-palmitoylation) is a common post-translational modification of eukaryotic proteins. In this review, we discuss the role of palmitoylation as a versatile protein sorting signal, regulating protein trafficking between distinct intracellular compartments and the micro-localization of proteins within membranes.

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M3 - Literature review

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JO - Molecular Membrane Biology

JF - Molecular Membrane Biology

IS - 1-2

ER -

The fat controller: roles of palmitoylation in intracellular protein trafficking and targeting to membrane microdomains (Review)

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