Abstract
The gene for human complement component C9 has been mapped to chromosome 5. This was achieved by using a novel application of the polymerase chain reaction to amplify specifically the human C9 gene on a background of rodent DNA in somatic cell hybrids. The assignment to chromosome 5 was confirmed by in situ hybridization to human metaphase chromosomes, giving a regional localization of 5p13.
| Original language | English |
|---|---|
| Pages (from-to) | 606-9 |
| Number of pages | 4 |
| Journal | Genomics |
| Volume | 4 |
| Issue number | 4 |
| Publication status | Published - 1989 |
Keywords / Materials (for Non-textual outputs)
- Animals
- Chromosome Mapping
- Chromosomes, Human, Pair 5
- Complement C9
- Cricetinae
- Cricetulus
- Gene Amplification
- Genes
- Humans
- Hybrid Cells
- Mice
- Rats