The genes coding for phosphoenolpyruvate carboxykinase-1 (PCK1) and neuronal nicotinic acetylcholine receptor alpha 4 subunit (CHRNA4) map to human chromosome 20, extending the known region of homology with mouse chromosome 2

A J Pilz, E Willer, S Povey, C M Abbott

Research output: Contribution to journalArticlepeer-review

Abstract

The mouse genes for cytosolic phosphoenolpyruvate carboxykinase-1 (Pck-1) and neuronal nicotinic acetylcholine receptor alpha 4 subunit (Acra-4) both map to distal chromosome 2 (Siracusa et al. 1989; Bessis et al. 1990). We have utilized Southern blot analysis on human/rodent somatic cell hybrids to map the human homologues of both of these genes, PCK1 and CHRNA4, to human chromosome 20.
Original languageEnglish
Pages (from-to)289-93
Number of pages5
JournalAnnals of human genetics
Volume56
Issue numberPt 4
Publication statusPublished - 1992

Keywords

  • Animals
  • Blotting, Southern
  • Chromosome Mapping
  • Chromosomes, Human, Pair 20
  • Cricetinae
  • Humans
  • Hybrid Cells
  • Mice
  • Phosphoenolpyruvate Carboxykinase (GTP)
  • Rats
  • Receptors, Nicotinic
  • Species Specificity

Fingerprint

Dive into the research topics of 'The genes coding for phosphoenolpyruvate carboxykinase-1 (PCK1) and neuronal nicotinic acetylcholine receptor alpha 4 subunit (CHRNA4) map to human chromosome 20, extending the known region of homology with mouse chromosome 2'. Together they form a unique fingerprint.

Cite this