The GUDMAP database - an online resource for genitourinary research

Simon D. Harding; Chris Armit; Jane Armstrong; Jane Brennan; Ying Cheng; Bernard Haggarty; Derek Houghton; Sue Lloyd-MacGilp; Xingjun Pi; Yogmatee Roochun; Mehran Sharghi; Christopher Tindal; Andrew P. McMahon; Brian Gottesman; Melissa H. Little; Kylie Georgas; Bruce J. Aronow; S. Steven Potter; Eric W. Brunskill; E. Michelle Southard-Smith; Cathy Mendelsohn; Richard A. Baldock; Jamie A. Davies; Duncan Davidson

doi:10.1242/dev.063594

The GUDMAP database - an online resource for genitourinary research

Simon D. Harding^*, Chris Armit, Jane Armstrong, Jane Brennan, Ying Cheng, Bernard Haggarty, Derek Houghton, Sue Lloyd-MacGilp, Xingjun Pi, Yogmatee Roochun, Mehran Sharghi, Christopher Tindal, Andrew P. McMahon, Brian Gottesman, Melissa H. Little, Kylie Georgas, Bruce J. Aronow, S. Steven Potter, Eric W. Brunskill, E. Michelle Southard-SmithCathy Mendelsohn, Richard A. Baldock, Jamie A. Davies, Duncan Davidson

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

The GenitoUrinary Development Molecular Anatomy Project (GUDMAP) is an international consortium working to generate gene expression data and transgenic mice. GUDMAP includes data from large-scale in situ hybridisation screens (wholemount and section) and microarray gene expression data of microdissected, laser-captured and FACS-sorted components of the developing mouse genitourinary (GU) system. These expression data are annotated using a high-resolution anatomy ontology specific to the developing murine GU system. GUDMAP data are freely accessible at www.gudmap.org via easy-to-use interfaces. This curated, high-resolution dataset serves as a powerful resource for biologists, clinicians and bioinformaticians interested in the developing urogenital system. This paper gives examples of how the data have been used to address problems in developmental biology and provides a primer for those wishing to use the database in their own research.

Original language	English
Pages (from-to)	2845-2853
Number of pages	9
Journal	Development
Volume	138
Issue number	13
DOIs	https://doi.org/10.1242/dev.063594
Publication status	Published - 1 Jul 2011

Keywords / Materials (for Non-textual outputs)

EMBRYO
In situ hybridisation
GENE-EXPRESSION ANALYSIS
Database
ARCHIVE
NEPHRON
PATTERNS
Gene expression
RESOLUTION
UPDATE
Microarray
MOUSE KIDNEY
REVEALS
Genitourinary
DEVELOPING KIDNEY

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10.1242/dev.063594

The GUDMAP database - an online resource for genitourinary research
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial Share Alike License (http://creativecommons.org/licenses/by-nc-sa/3.0), which permits unrestricted non-commercial use, distribution and reproduction in any medium provided that the original work is properly cited and all further distributions of the work or adaptation are subject to the same Creative Commons License terms.
Final published version, 1.67 MB

http://dev.biologists.org/content/138/13/2845

Cite this

Harding, S. D., Armit, C., Armstrong, J., Brennan, J., Cheng, Y., Haggarty, B., Houghton, D., Lloyd-MacGilp, S., Pi, X., Roochun, Y., Sharghi, M., Tindal, C., McMahon, A. P., Gottesman, B., Little, M. H., Georgas, K., Aronow, B. J., Potter, S. S., Brunskill, E. W., ... Davidson, D. (2011). The GUDMAP database - an online resource for genitourinary research. Development, 138(13), 2845-2853. https://doi.org/10.1242/dev.063594

@article{d6dfa06a4f8844fd8572b78578382f8f,

title = "The GUDMAP database - an online resource for genitourinary research",

abstract = "The GenitoUrinary Development Molecular Anatomy Project (GUDMAP) is an international consortium working to generate gene expression data and transgenic mice. GUDMAP includes data from large-scale in situ hybridisation screens (wholemount and section) and microarray gene expression data of microdissected, laser-captured and FACS-sorted components of the developing mouse genitourinary (GU) system. These expression data are annotated using a high-resolution anatomy ontology specific to the developing murine GU system. GUDMAP data are freely accessible at www.gudmap.org via easy-to-use interfaces. This curated, high-resolution dataset serves as a powerful resource for biologists, clinicians and bioinformaticians interested in the developing urogenital system. This paper gives examples of how the data have been used to address problems in developmental biology and provides a primer for those wishing to use the database in their own research.",

keywords = "EMBRYO, In situ hybridisation, GENE-EXPRESSION ANALYSIS, Database, ARCHIVE, NEPHRON, PATTERNS, Gene expression, RESOLUTION, UPDATE, Microarray, MOUSE KIDNEY, REVEALS, Genitourinary, DEVELOPING KIDNEY",

author = "Harding, {Simon D.} and Chris Armit and Jane Armstrong and Jane Brennan and Ying Cheng and Bernard Haggarty and Derek Houghton and Sue Lloyd-MacGilp and Xingjun Pi and Yogmatee Roochun and Mehran Sharghi and Christopher Tindal and McMahon, {Andrew P.} and Brian Gottesman and Little, {Melissa H.} and Kylie Georgas and Aronow, {Bruce J.} and Potter, {S. Steven} and Brunskill, {Eric W.} and Southard-Smith, {E. Michelle} and Cathy Mendelsohn and Baldock, {Richard A.} and Davies, {Jamie A.} and Duncan Davidson",

year = "2011",

month = jul,

day = "1",

doi = "10.1242/dev.063594",

language = "English",

volume = "138",

pages = "2845--2853",

journal = "Development",

issn = "0950-1991",

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Harding, SD, Armit, C, Armstrong, J, Brennan, J, Cheng, Y, Haggarty, B, Houghton, D, Lloyd-MacGilp, S, Pi, X, Roochun, Y, Sharghi, M, Tindal, C, McMahon, AP, Gottesman, B, Little, MH, Georgas, K, Aronow, BJ, Potter, SS, Brunskill, EW, Southard-Smith, EM, Mendelsohn, C, Baldock, RA, Davies, JA & Davidson, D 2011, 'The GUDMAP database - an online resource for genitourinary research', Development, vol. 138, no. 13, pp. 2845-2853. https://doi.org/10.1242/dev.063594

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T1 - The GUDMAP database - an online resource for genitourinary research

AU - Harding, Simon D.

AU - Armit, Chris

AU - Armstrong, Jane

AU - Brennan, Jane

AU - Cheng, Ying

AU - Haggarty, Bernard

AU - Houghton, Derek

AU - Lloyd-MacGilp, Sue

AU - Pi, Xingjun

AU - Roochun, Yogmatee

AU - Sharghi, Mehran

AU - Tindal, Christopher

AU - McMahon, Andrew P.

AU - Gottesman, Brian

AU - Little, Melissa H.

AU - Georgas, Kylie

AU - Aronow, Bruce J.

AU - Potter, S. Steven

AU - Brunskill, Eric W.

AU - Southard-Smith, E. Michelle

AU - Mendelsohn, Cathy

AU - Baldock, Richard A.

AU - Davies, Jamie A.

AU - Davidson, Duncan

PY - 2011/7/1

Y1 - 2011/7/1

N2 - The GenitoUrinary Development Molecular Anatomy Project (GUDMAP) is an international consortium working to generate gene expression data and transgenic mice. GUDMAP includes data from large-scale in situ hybridisation screens (wholemount and section) and microarray gene expression data of microdissected, laser-captured and FACS-sorted components of the developing mouse genitourinary (GU) system. These expression data are annotated using a high-resolution anatomy ontology specific to the developing murine GU system. GUDMAP data are freely accessible at www.gudmap.org via easy-to-use interfaces. This curated, high-resolution dataset serves as a powerful resource for biologists, clinicians and bioinformaticians interested in the developing urogenital system. This paper gives examples of how the data have been used to address problems in developmental biology and provides a primer for those wishing to use the database in their own research.

AB - The GenitoUrinary Development Molecular Anatomy Project (GUDMAP) is an international consortium working to generate gene expression data and transgenic mice. GUDMAP includes data from large-scale in situ hybridisation screens (wholemount and section) and microarray gene expression data of microdissected, laser-captured and FACS-sorted components of the developing mouse genitourinary (GU) system. These expression data are annotated using a high-resolution anatomy ontology specific to the developing murine GU system. GUDMAP data are freely accessible at www.gudmap.org via easy-to-use interfaces. This curated, high-resolution dataset serves as a powerful resource for biologists, clinicians and bioinformaticians interested in the developing urogenital system. This paper gives examples of how the data have been used to address problems in developmental biology and provides a primer for those wishing to use the database in their own research.

KW - EMBRYO

KW - In situ hybridisation

KW - GENE-EXPRESSION ANALYSIS

KW - Database

KW - ARCHIVE

KW - NEPHRON

KW - PATTERNS

KW - Gene expression

KW - RESOLUTION

KW - UPDATE

KW - Microarray

KW - MOUSE KIDNEY

KW - REVEALS

KW - Genitourinary

KW - DEVELOPING KIDNEY

UR - http://www.scopus.com/inward/record.url?scp=79958171563&partnerID=8YFLogxK

U2 - 10.1242/dev.063594

DO - 10.1242/dev.063594

M3 - Article

SN - 0950-1991

VL - 138

SP - 2845

EP - 2853

JO - Development

JF - Development

IS - 13

ER -

The GUDMAP database - an online resource for genitourinary research

Abstract

Keywords / Materials (for Non-textual outputs)

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Murine Atlas of Genitourinary Development (MAGUD)

Cite this

The GUDMAP database - an online resource for genitourinary research

Abstract

Keywords / Materials (for Non-textual outputs)

Access to Document

Other files and links

Fingerprint

Projects

Murine Atlas of Genitourinary Development (MAGUD)

Cite this