The Hepatic Compensatory Response to Elevated Systemic Sulfide Promotes Diabetes

Roderick Nicholas Carter; Matthew T G Gibbins; Martin E. Barrios-Llerena; Stephen E Wilkie; Peter L.  Freddolino; Marouane  Libiad; Victor  Vitvitsky; Barry Emerson; Thierry Le Bihan; Madara  Brice; Huizhong Su; Scott G. Denham; Natalie Z M Homer; Clare McFadden; Anne  Tailleux; Nourdine  Faresse; Thierry  Sulpice; Francois  Briand; Thomas H Gillingwater; Kyo  Han Ahn; Subhankar Singha; Claire  McMaster; Richard C Hartley; Bart Staels; Gillian A Gray; Andrew J Finch; Colin Selman; Ruma  Banerjee; Nicholas M Morton

doi:10.1016/j.celrep.2021.109958

The Hepatic Compensatory Response to Elevated Systemic Sulfide Promotes Diabetes

Roderick Nicholas Carter
, Matthew T G Gibbins
, Martin E. Barrios-Llerena
, Stephen E Wilkie
, Peter L. Freddolino
, Marouane Libiad
, Victor Vitvitsky
, Barry Emerson
, Thierry Le Bihan
, Madara Brice
, Huizhong Su
, Scott G. Denham
, Natalie Z M Homer
, Clare McFadden
, Anne Tailleux
, Nourdine Faresse
, Thierry Sulpice
, Francois Briand
, Thomas H Gillingwater
, Kyo Han Ahn

Subhankar Singha, Claire McMaster, Richard C Hartley, Bart Staels, Gillian A Gray, Andrew J Finch, Colin Selman, Ruma Banerjee, Nicholas M Morton^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Original language	English
Journal	Cell Reports
DOIs	https://doi.org/10.1016/j.celrep.2021.109958
Publication status	Published - 9 Nov 2021

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10.1016/j.celrep.2021.109958

CELL-REPORTS-D-21-00011_R3Accepted author manuscript, 5.05 MB

Delineating the anti-diabetic mechanisms of thiosulfate sulfurtransferase activity.
Morton, N. (Principal Investigator), Carter, R. (Co-investigator) & Fallowfield, J. (Co-investigator)
UK-based charities
1/07/18 → 30/12/21
Project: Research
Exploiting the population isolate GWAS "jack-pot effect": Transgene modelling of a novel human visceral fat and blood pressure lowering gene.
Morton, N. (Principal Investigator)
UK-based charities
22/09/16 → 21/07/18
Project: Research

TST knockout liver proteome iTRAQ and persulfidome
Morton, N. (Creator), PRIDE database hosted by European Bioinformatics Institute, EBI, 9 Nov 2021
https://www.ebi.ac.uk/pride/archive and one more link, https://www.ebi.ac.uk/pride/archive/projects/PXD028909 (show fewer)
Dataset

Edinburgh Clinical Research Facility Mass Spectrometry Core in the QMRI
Homer, N. (Manager), Denham, S. (Other) & Simpson, J. (Other)
School of Neurological and Cardiovascular Sciences
Facility/equipment: Facility

Cite this

Nicholas Carter, R., Gibbins, M. T. G., Barrios-Llerena, M. E., Wilkie, S. E., Freddolino, P. L., Libiad, M., Vitvitsky, V., Emerson, B., Le Bihan, T., Brice, M., Su, H., Denham, S. G., Homer, N. Z. M., McFadden, C., Tailleux, A., Faresse, N., Sulpice, T., Briand, F., Gillingwater, T. H., ... Morton, N. M. (2021). The Hepatic Compensatory Response to Elevated Systemic Sulfide Promotes Diabetes. Cell Reports. https://doi.org/10.1016/j.celrep.2021.109958

@article{8c9c51c95aa24929b9e8ed9e16e5cf97,

title = "The Hepatic Compensatory Response to Elevated Systemic Sulfide Promotes Diabetes",

author = "\{Nicholas Carter\}, Roderick and Gibbins, \{Matthew T G\} and Barrios-Llerena, \{Martin E.\} and Wilkie, \{Stephen E\} and Freddolino, \{Peter L.\} and Marouane Libiad and Victor Vitvitsky and Barry Emerson and \{Le Bihan\}, Thierry and Madara Brice and Huizhong Su and Denham, \{Scott G.\} and Homer, \{Natalie Z M\} and Clare McFadden and Anne Tailleux and Nourdine Faresse and Thierry Sulpice and Francois Briand and Gillingwater, \{Thomas H\} and \{Han Ahn\}, Kyo and Subhankar Singha and Claire McMaster and Hartley, \{Richard C\} and Bart Staels and Gray, \{Gillian A\} and \{J Finch\}, Andrew and Colin Selman and Ruma Banerjee and Morton, \{Nicholas M\}",

year = "2021",

month = nov,

day = "9",

doi = "10.1016/j.celrep.2021.109958",

language = "English",

journal = "Cell Reports",

issn = "2211-1247",

publisher = "Elsevier",

}

Nicholas Carter, R, Gibbins, MTG, Barrios-Llerena, ME, Wilkie, SE, Freddolino, PL, Libiad, M, Vitvitsky, V, Emerson, B, Le Bihan, T, Brice, M, Su, H, Denham, SG , Homer, NZM, McFadden, C, Tailleux, A, Faresse, N, Sulpice, T, Briand, F, Gillingwater, TH, Han Ahn, K, Singha, S, McMaster, C, Hartley, RC, Staels, B, Gray, GA, J Finch, A, Selman, C, Banerjee, R & Morton, NM 2021, 'The Hepatic Compensatory Response to Elevated Systemic Sulfide Promotes Diabetes', Cell Reports. https://doi.org/10.1016/j.celrep.2021.109958

TY - JOUR

T1 - The Hepatic Compensatory Response to Elevated Systemic Sulfide Promotes Diabetes

AU - Nicholas Carter, Roderick

AU - Gibbins, Matthew T G

AU - Barrios-Llerena, Martin E.

AU - Wilkie, Stephen E

AU - Freddolino, Peter L.

AU - Libiad, Marouane

AU - Vitvitsky, Victor

AU - Emerson, Barry

AU - Le Bihan, Thierry

AU - Brice, Madara

AU - Su, Huizhong

AU - Denham, Scott G.

AU - Homer, Natalie Z M

AU - McFadden, Clare

AU - Tailleux, Anne

AU - Faresse, Nourdine

AU - Sulpice, Thierry

AU - Briand, Francois

AU - Gillingwater, Thomas H

AU - Han Ahn, Kyo

AU - Singha, Subhankar

AU - McMaster, Claire

AU - Hartley, Richard C

AU - Staels, Bart

AU - Gray, Gillian A

AU - J Finch, Andrew

AU - Selman, Colin

AU - Banerjee, Ruma

AU - Morton, Nicholas M

PY - 2021/11/9

Y1 - 2021/11/9

U2 - 10.1016/j.celrep.2021.109958

DO - 10.1016/j.celrep.2021.109958

M3 - Article

SN - 2211-1247

JO - Cell Reports

JF - Cell Reports

ER -

The Hepatic Compensatory Response to Elevated Systemic Sulfide Promotes Diabetes

Access to Document

Projects

Delineating the anti-diabetic mechanisms of thiosulfate sulfurtransferase activity.

Exploiting the population isolate GWAS "jack-pot effect": Transgene modelling of a novel human visceral fat and blood pressure lowering gene.

Datasets

TST knockout liver proteome iTRAQ and persulfidome

Equipment

Edinburgh Clinical Research Facility Mass Spectrometry Core in the QMRI

Cite this