The human-specific action of intermedilysin, a homolog of streptolysin O, is dictated by domain 4 of the protein

Hideaki Nagamune*, Kazuto Ohkura, Akiko Sukeno, Graeme Cowan, Timothy J. Mitchell, Wataru Ito, Ooki Ohnishi, Kanako Hattori, Miki Yamato, Katsuhiko Hirota, Yoichiro Miyake, Takuya Maeda, Hiroki Kourai

*Corresponding author for this work

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Biochemistry, Genetics and Molecular Biology

Pharmacology, Toxicology and Pharmaceutical Science