The Impact of Deep Brain Stimulation on Sleep and Olfactory Function in Parkinson's Disease

David P Breen; Hu Liang Low; Anjum Misbahuddin

doi:10.2174/1874205X01509010070

The Impact of Deep Brain Stimulation on Sleep and Olfactory Function in Parkinson's Disease

David P Breen, Hu Liang Low, Anjum Misbahuddin

Research output: Contribution to journal › Article › peer-review

Abstract

OBJECTIVE: Relatively little is known about the effects of deep brain stimulation on non-motor symptoms. The aim of this pilot study was to assess the impact of deep brain stimulation on sleep and olfactory function in Parkinson's disease.

METHODS: Subjective sleep quality and olfactory testing were performed on 11 consecutive Parkinson's disease patients (eight men and three women) undergoing bilateral subthalamic nucleus stimulation. All patients consented to undergo clinical assessments prior to the procedure, and at regular intervals afterwards.

RESULTS: Subjective sleep quality improved at six months following deep brain stimulation and this benefit was sustained in the majority of patients at later follow-up assessments. There was no significant change in olfactory function following deep brain stimulation.

CONCLUSIONS: In addition to having beneficial effects on motor function and quality of life, bilateral subthalamic nucleus stimulation improves subjective sleep quality in Parkinson's disease.

Original language	English
Pages (from-to)	70-2
Number of pages	3
Journal	The Open Neurology Journal
Volume	9
DOIs	https://doi.org/10.2174/1874205X01509010070
Publication status	Published - 2015

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title = "The Impact of Deep Brain Stimulation on Sleep and Olfactory Function in Parkinson's Disease",

abstract = "OBJECTIVE: Relatively little is known about the effects of deep brain stimulation on non-motor symptoms. The aim of this pilot study was to assess the impact of deep brain stimulation on sleep and olfactory function in Parkinson's disease.METHODS: Subjective sleep quality and olfactory testing were performed on 11 consecutive Parkinson's disease patients (eight men and three women) undergoing bilateral subthalamic nucleus stimulation. All patients consented to undergo clinical assessments prior to the procedure, and at regular intervals afterwards.RESULTS: Subjective sleep quality improved at six months following deep brain stimulation and this benefit was sustained in the majority of patients at later follow-up assessments. There was no significant change in olfactory function following deep brain stimulation.CONCLUSIONS: In addition to having beneficial effects on motor function and quality of life, bilateral subthalamic nucleus stimulation improves subjective sleep quality in Parkinson's disease.",

author = "Breen, {David P} and Low, {Hu Liang} and Anjum Misbahuddin",

year = "2015",

doi = "10.2174/1874205X01509010070",

language = "English",

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journal = "The Open Neurology Journal",

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T1 - The Impact of Deep Brain Stimulation on Sleep and Olfactory Function in Parkinson's Disease

AU - Breen, David P

AU - Low, Hu Liang

AU - Misbahuddin, Anjum

PY - 2015

Y1 - 2015

N2 - OBJECTIVE: Relatively little is known about the effects of deep brain stimulation on non-motor symptoms. The aim of this pilot study was to assess the impact of deep brain stimulation on sleep and olfactory function in Parkinson's disease.METHODS: Subjective sleep quality and olfactory testing were performed on 11 consecutive Parkinson's disease patients (eight men and three women) undergoing bilateral subthalamic nucleus stimulation. All patients consented to undergo clinical assessments prior to the procedure, and at regular intervals afterwards.RESULTS: Subjective sleep quality improved at six months following deep brain stimulation and this benefit was sustained in the majority of patients at later follow-up assessments. There was no significant change in olfactory function following deep brain stimulation.CONCLUSIONS: In addition to having beneficial effects on motor function and quality of life, bilateral subthalamic nucleus stimulation improves subjective sleep quality in Parkinson's disease.

AB - OBJECTIVE: Relatively little is known about the effects of deep brain stimulation on non-motor symptoms. The aim of this pilot study was to assess the impact of deep brain stimulation on sleep and olfactory function in Parkinson's disease.METHODS: Subjective sleep quality and olfactory testing were performed on 11 consecutive Parkinson's disease patients (eight men and three women) undergoing bilateral subthalamic nucleus stimulation. All patients consented to undergo clinical assessments prior to the procedure, and at regular intervals afterwards.RESULTS: Subjective sleep quality improved at six months following deep brain stimulation and this benefit was sustained in the majority of patients at later follow-up assessments. There was no significant change in olfactory function following deep brain stimulation.CONCLUSIONS: In addition to having beneficial effects on motor function and quality of life, bilateral subthalamic nucleus stimulation improves subjective sleep quality in Parkinson's disease.

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DO - 10.2174/1874205X01509010070

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JO - The Open Neurology Journal

JF - The Open Neurology Journal

SN - 1874-205X

ER -

The Impact of Deep Brain Stimulation on Sleep and Olfactory Function in Parkinson's Disease

Abstract

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