The importance of asking “how and why?” in natural product structure elucidation

Patrick D. Brown; Andrew L. Lawrence

doi:10.1039/C7NP00025A

The importance of asking “how and why?” in natural product structure elucidation

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Abstract

This review highlights why careful consideration of the biosynthetic origin (the how) and the biological function (the why) of a natural product can be so useful during the determination of its structure. Recent examples of structural reassignments inspired by biosynthetic and functional insights will be presented. This review will demonstrate the importance of viewing the origin, structure and function of a natural product as intertwined threads of a single story, best viewed as a whole rather than as discrete topics.

Original language	English
Journal	Natural product reports
Early online date	29 Aug 2017
DOIs	https://doi.org/10.1039/C7NP00025A https://doi.org/10.1039/C7NP00025A
Publication status	E-pub ahead of print - 29 Aug 2017

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20170831 Lawrence NPR Final Author DraftAccepted author manuscript, 693 KBLicence: Creative Commons: Attribution (CC-BY)

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The importance of asking “how and why?” in natural product structure elucidation

Abstract

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