Abstract / Description of output
A cDNA corresponding to canine IL-2 has been isolated and sequenced. The cDNA was synthesised using RT-PCR, with oligonucleotide primers designed from conserved regions of published IL-2 sequences. The cDNA encodes a predicted full length IL-2 protein of 155 amino-acids. At the nucleic acid level, the canine cDNA shows 92, 88, 88, 82 and 74% homology to published sequences of feline, human, equine, bovine and murine IL-2, respectively. The derived protein shows 90, 86, 85, 76 and 75% similarity to feline, human, equine, murine and bovine IL-2 homologs.
| Original language | English |
|---|---|
| Pages (from-to) | 177-80 |
| Number of pages | 4 |
| Journal | DNA Sequence |
| Volume | 5 |
| Issue number | 3 |
| Publication status | Published - 1995 |
Keywords / Materials (for Non-textual outputs)
- Amino Acid Sequence
- Animals
- Base Sequence
- Cats
- Cattle
- Cloning, Molecular
- DNA, Complementary
- Dogs
- Horses
- Humans
- Interleukin-2
- Molecular Sequence Data
- Polymerase Chain Reaction
- Sequence Alignment