The LKB1-AMPK-α1 signalling pathway triggers hypoxic pulmonary vasoconstriction downstream of mitochondria

Javier Moral-Sanz; Sophronia A. Lewis; Sandy MacMillan; Fiona A. Ross; Adrian Thomson; Benoit Viollet; Marc Foretz; Carmel Moran; D. Grahame Hardie; A. Mark Evans

doi:10.1126/scisignal.aau0296

The LKB1-AMPK-α1 signalling pathway triggers hypoxic pulmonary vasoconstriction downstream of mitochondria

Javier Moral-Sanz, Sophronia A. Lewis, Sandy MacMillan, Fiona A. Ross, Adrian Thomson, Benoit Viollet, Marc Foretz, Carmel Moran, D. Grahame Hardie, A. Mark Evans

Research output: Contribution to journal › Article › peer-review

Original language	English
Journal	Science Signaling
Volume	11
Issue number	550
DOIs	https://doi.org/10.1126/scisignal.aau0296
Publication status	Published - 2 Oct 2018

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10.1126/scisignal.aau0296

Moral-Sanz et al 2018 Accepted version
This is the author's version of the work. It is posted here by permission of the AAAS for personal use, not for redistribution. The definitive version was published in Science Signalling: http://stke.sciencemag.org/content/11/550/eaau0296
Accepted author manuscript, 0.99 MB

Angiotensin II and pulmonary arterial hypertension:
Evans, M.
UK-based charities
1/06/13 → 31/05/18
Project: Research
Is AMP activated protein kinase sufficent and necessary for calcium signalling by Hypoxia in oxygen-sensing cells?
Evans, M.
UK-based charities
1/01/09 → 31/12/13
Project: Research

Carmel Moran
- carmel.moraned.acuk
- Deanery of Clinical Sciences - Personal Chair of Preclinical Ultrasound
- Centre for Cardiovascular Science
- Edinburgh Imaging
Person: Academic: Research Active

Cite this

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title = "The LKB1-AMPK-α1 signalling pathway triggers hypoxic pulmonary vasoconstriction downstream of mitochondria",

author = "Javier Moral-Sanz and Lewis, {Sophronia A.} and Sandy MacMillan and Ross, {Fiona A.} and Adrian Thomson and Benoit Viollet and Marc Foretz and Carmel Moran and Hardie, {D. Grahame} and Evans, {A. Mark}",

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AU - Moral-Sanz, Javier

AU - Lewis, Sophronia A.

AU - MacMillan, Sandy

AU - Ross, Fiona A.

AU - Thomson, Adrian

AU - Viollet, Benoit

AU - Foretz, Marc

AU - Moran, Carmel

AU - Hardie, D. Grahame

AU - Evans, A. Mark

PY - 2018/10/2

Y1 - 2018/10/2

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DO - 10.1126/scisignal.aau0296

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SN - 1945-0877

VL - 11

JO - Science Signaling

JF - Science Signaling

IS - 550

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The LKB1-AMPK-α1 signalling pathway triggers hypoxic pulmonary vasoconstriction downstream of mitochondria

Access to Document

Projects

Angiotensin II and pulmonary arterial hypertension:

Is AMP activated protein kinase sufficent and necessary for calcium signalling by Hypoxia in oxygen-sensing cells?

Profiles

Carmel Moran

Cite this