The long journey towards standards for engineering biosystems: Are the Molecular Biology and the Biotech communities ready to standardise?

Jacob Beal, Angel Goñi-Moreno, Chris Myers, Ariel Hecht, María Del Carmen de Vicente, Maria Parco, Markus Schmidt, Kenneth Timmis, Geoff Baldwin, Steffi Friedrichs, Paul Freemont, Daisuke Kiga, Elena Ordozgoiti, Maja Rennig, Leonardo Rios, Kristie Tanner, Víctor de Lorenzo, Manuel Porcar

Research output: Contribution to journalArticlepeer-review

Abstract

Standards are the basis of technology: they allow rigorous description and exact measurement of properties, reliable reproducibility and a common “language” that enables different communities to work together. Molecular biology was in part created by physicists; yet, the field did not inherit the focus on the quantitation, the definition of system boundaries and the robust, unequivocal language that is characteristic of the other natural sciences. However, synthetic biology (SynBio) increasingly requires scientific, technical, operational and semantic standards for the field to become a full‐fledged engineering discipline with a high level of accuracy in the design, manufacturing and performance of biological artefacts. Although the benefits of adopting standards are clear, the community is still largely reluctant to accept them, owing to concerns about adoption costs and losses in flexibility.

Original languageEnglish
Pages (from-to)e50521
JournalEMBO Reports
Volume21
Issue number5
Early online date26 Apr 2020
DOIs
Publication statusPublished - 6 May 2020

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