The long-term sequelae of COVID-19: an international consensus on research priorities for patients with pre-existing and new-onset airways disease

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Abstract

The recently described persistent ill health after acute COVID-19, so called “long COVID” has emerged as a major concern. We conducted a prioritisation exercise to identify research priorities for the long term effects of COVID-19 in airways diseases. A total of 202 international experts were invited to submit a minimum of three research ideas. Following a two-phase internal review process, a final list of 98 research questions was scored by 48 experts. The top ranked research question proposed investigating the relationship between an admission prognostic score and post-discharge morbidity at 3- and 12-months in groups of patients with and without pre-existing airways diseases. High scores were also assigned to comparing those two groups of patients in prevalence and severity of post-COVID-19 fatigue, sarcopenia, anxiety, depression and risk of future cardiovascular complications. Our approach has allowed development of a priority list that may inform future research studies and funding decisions. This prioritisation process can be adapted to other areas in long COVID.

Original languageEnglish
JournalThe Lancet Respiratory Medicine
Early online date17 Aug 2021
DOIs
Publication statusE-pub ahead of print - 17 Aug 2021

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