Abstract / Description of output
3-Methoxy-5-(2-thienyl) thiophene-2-carboxaldehyde and 3-methoxy-l-methyl-5-(2-thienyl)pyrrole-2-carboxaldehyde were prepared from the appropriate 3-hydroxypyrrole or 3-hydroxythiophene by regioselective O-alkylation and formylation. Condensation of these aldehydes with activated pyrroles in the presence of phosphoryl chloride provides analogues of prodigiosin, which differ from the natural products in the nature of the heteroatoms.
Original language | English |
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Pages (from-to) | 1707-1711 |
Number of pages | 5 |
Journal | Synthesis: Journal of Synthetic Organic Chemistry |
Issue number | 10 |
DOIs | |
Publication status | Published - May 2010 |