The mononuclear phagocyte system of the mouse defined by immunohistochemical localization of antigen F4/80: macrophages of endocrine organs

D A Hume, D Halpin, H Charlton, S Gordon

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Macrophages of endocrine organs have been identified by immunohistochemical localization of the macrophage-specific antigen F4/80. F4/80+ cells line vascular sinuses and capillaries in anterior and posterior pituitary, adrenal cortex, corpus luteum, parathyroid, pineal gland, and islets of Langerhans. In testis approximately 20% of interstitial cells are F4/80+. F4/80+ cells infiltrate corpus luteum in increased numbers during luteolysis.
Original languageEnglish
Pages (from-to)4174-7
Number of pages4
JournalProceedings of the National Academy of Sciences (PNAS)
Volume81
Issue number13
Publication statusPublished - Jul 1984

Keywords / Materials (for Non-textual outputs)

  • Adrenal Cortex
  • Animals
  • Antigens, Surface
  • Female
  • Immunoassay
  • Islets of Langerhans
  • Macrophages
  • Male
  • Mice
  • Monocytes
  • Ovary
  • Parathyroid Glands
  • Phagocytosis
  • Pineal Gland
  • Pituitary Gland
  • Testis
  • Thyroid Gland
  • Tissue Distribution

Fingerprint

Dive into the research topics of 'The mononuclear phagocyte system of the mouse defined by immunohistochemical localization of antigen F4/80: macrophages of endocrine organs'. Together they form a unique fingerprint.

Cite this