The neonatal window of opportunity - early priming for life

Harald Renz; Becky D Adkins; Sina Bartfeld; Richard S Blumberg; Donna L Farber; Johan Garssen; Peter Ghazal; David J Hackam; Benjamin J Marsland; Kathy D McCoy; John Penders; Immo Prinz; Valerie Verhasselt; Erika von Mutius; Jeffrey N Weiser; Duane R Wesemann; Mathias W Hornef

doi:10.1016/j.jaci.2017.11.019

The neonatal window of opportunity - early priming for life

Harald Renz, Becky D Adkins, Sina Bartfeld, Richard S Blumberg, Donna L Farber, Johan Garssen, Peter Ghazal, David J Hackam, Benjamin J Marsland, Kathy D McCoy, John Penders, Immo Prinz, Valerie Verhasselt, Erika von Mutius, Jeffrey N Weiser, Duane R Wesemann, Mathias W Hornef

Research output: Contribution to journal › Article › peer-review

Abstract

The concept of the neonatal window of opportunity assigns the early postnatal period a critical role for life-long host-microbial and immune homeostasis. It is supported by epidemiological evidence that links postnatal environmental exposure with disease susceptibility and mechanisms in the neonate host that facilitate the postnatal transposition, establish a stable microbiome and promote immune maturation. During the conference on "The neonatal window of opportunity - early priming for life", postnatal microbiome and immune maturation, epidemiological evidence and fundamental mechanisms were discussed to identify new targets for future preventive and interventional measures.

Original language	English
Journal	Journal of Allergy and Clinical Immunology
Early online date	14 Dec 2017
DOIs	https://doi.org/10.1016/j.jaci.2017.11.019
Publication status	E-pub ahead of print - 14 Dec 2017

Keywords / Materials (for Non-textual outputs)

Editorial

Access to Document

10.1016/j.jaci.2017.11.019

Cite this

Renz, H., Adkins, B. D., Bartfeld, S., Blumberg, R. S., Farber, D. L., Garssen, J., Ghazal, P., Hackam, D. J., Marsland, B. J., McCoy, K. D., Penders, J., Prinz, I., Verhasselt, V., von Mutius, E., Weiser, J. N., Wesemann, D. R., & Hornef, M. W. (2017). The neonatal window of opportunity - early priming for life. Journal of Allergy and Clinical Immunology. Advance online publication. https://doi.org/10.1016/j.jaci.2017.11.019

@article{77acba43a77d4b83a04b8af7354955d7,

title = "The neonatal window of opportunity - early priming for life",

abstract = "The concept of the neonatal window of opportunity assigns the early postnatal period a critical role for life-long host-microbial and immune homeostasis. It is supported by epidemiological evidence that links postnatal environmental exposure with disease susceptibility and mechanisms in the neonate host that facilitate the postnatal transposition, establish a stable microbiome and promote immune maturation. During the conference on {"}The neonatal window of opportunity - early priming for life{"}, postnatal microbiome and immune maturation, epidemiological evidence and fundamental mechanisms were discussed to identify new targets for future preventive and interventional measures.",

keywords = "Editorial",

author = "Harald Renz and Adkins, {Becky D} and Sina Bartfeld and Blumberg, {Richard S} and Farber, {Donna L} and Johan Garssen and Peter Ghazal and Hackam, {David J} and Marsland, {Benjamin J} and McCoy, {Kathy D} and John Penders and Immo Prinz and Valerie Verhasselt and {von Mutius}, Erika and Weiser, {Jeffrey N} and Wesemann, {Duane R} and Hornef, {Mathias W}",

note = "Copyright {\textcopyright} 2017. Published by Elsevier Inc.",

year = "2017",

month = dec,

day = "14",

doi = "10.1016/j.jaci.2017.11.019",

language = "English",

journal = "Journal of Allergy and Clinical Immunology",

issn = "0091-6749",

publisher = "Elsevier Inc.",

}

TY - JOUR

T1 - The neonatal window of opportunity - early priming for life

AU - Renz, Harald

AU - Adkins, Becky D

AU - Bartfeld, Sina

AU - Blumberg, Richard S

AU - Farber, Donna L

AU - Garssen, Johan

AU - Ghazal, Peter

AU - Hackam, David J

AU - Marsland, Benjamin J

AU - McCoy, Kathy D

AU - Penders, John

AU - Prinz, Immo

AU - Verhasselt, Valerie

AU - von Mutius, Erika

AU - Weiser, Jeffrey N

AU - Wesemann, Duane R

AU - Hornef, Mathias W

PY - 2017/12/14

Y1 - 2017/12/14

N2 - The concept of the neonatal window of opportunity assigns the early postnatal period a critical role for life-long host-microbial and immune homeostasis. It is supported by epidemiological evidence that links postnatal environmental exposure with disease susceptibility and mechanisms in the neonate host that facilitate the postnatal transposition, establish a stable microbiome and promote immune maturation. During the conference on "The neonatal window of opportunity - early priming for life", postnatal microbiome and immune maturation, epidemiological evidence and fundamental mechanisms were discussed to identify new targets for future preventive and interventional measures.

AB - The concept of the neonatal window of opportunity assigns the early postnatal period a critical role for life-long host-microbial and immune homeostasis. It is supported by epidemiological evidence that links postnatal environmental exposure with disease susceptibility and mechanisms in the neonate host that facilitate the postnatal transposition, establish a stable microbiome and promote immune maturation. During the conference on "The neonatal window of opportunity - early priming for life", postnatal microbiome and immune maturation, epidemiological evidence and fundamental mechanisms were discussed to identify new targets for future preventive and interventional measures.

KW - Editorial

U2 - 10.1016/j.jaci.2017.11.019

DO - 10.1016/j.jaci.2017.11.019

M3 - Article

C2 - 29247715

SN - 0091-6749

JO - Journal of Allergy and Clinical Immunology

JF - Journal of Allergy and Clinical Immunology

ER -

The neonatal window of opportunity - early priming for life

Abstract

Keywords / Materials (for Non-textual outputs)

Access to Document

Fingerprint

Cite this