The Open-Access European Prevention of Alzheimer’s Dementia (EPAD) MRI dataset and processing workflow

Luigi Lorenzini; Silvia Ingala; Alle Meije Wink; Joost P.a. Kuijer; Viktor Wottschel; Mathijs Dijsselhof; Carole H. Sudre; Sven Haller; José Luis Molinuevo; Juan Domingo Gispert; David M. Cash; David L. Thomas; Sjoerd B. Vos; Ferran Prados; Jan Petr; Robin Wolz; Alessandro Palombit; Adam J. Schwarz; Gaël Chételat; Pierre Payoux; Carol Di Perri; Joanna M. Wardlaw; Giovanni B. Frisoni; Christopher Foley; Nick C. Fox; Craig Ritchie; Cyril Pernet; Adam Waldman; Frederik Barkhof; Henk J.m.m. Mutsaerts

doi:10.1016/j.nicl.2022.103106

The Open-Access European Prevention of Alzheimer’s Dementia (EPAD) MRI dataset and processing workflow

Luigi Lorenzini, Silvia Ingala, Alle Meije Wink, Joost P.a. Kuijer, Viktor Wottschel, Mathijs Dijsselhof, Carole H. Sudre, Sven Haller, José Luis Molinuevo, Juan Domingo Gispert, David M. Cash, David L. Thomas, Sjoerd B. Vos, Ferran Prados, Jan Petr, Robin Wolz, Alessandro Palombit, Adam J. Schwarz, Gaël Chételat, Pierre PayouxCarol Di Perri, Joanna M. Wardlaw, Giovanni B. Frisoni, Christopher Foley, Nick C. Fox, Craig Ritchie, Cyril Pernet, Adam Waldman, Frederik Barkhof, Henk J.m.m. Mutsaerts

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	103106
Journal	NeuroImage: Clinical
Volume	35
Early online date	7 Jul 2022
DOIs	https://doi.org/10.1016/j.nicl.2022.103106
Publication status	E-pub ahead of print - 7 Jul 2022

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https://linkinghub.elsevier.com/retrieve/pii/S2213158222001711

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Lorenzini, L., Ingala, S., Wink, A. M., Kuijer, J. P. A., Wottschel, V., Dijsselhof, M., Sudre, C. H., Haller, S., Molinuevo, J. L., Gispert, J. D., Cash, D. M., Thomas, D. L., Vos, S. B., Prados, F., Petr, J., Wolz, R., Palombit, A., Schwarz, A. J., Chételat, G., ... Mutsaerts, H. J. M. M. (2022). The Open-Access European Prevention of Alzheimer’s Dementia (EPAD) MRI dataset and processing workflow. NeuroImage: Clinical, 35, 103106. Advance online publication. https://doi.org/10.1016/j.nicl.2022.103106

@article{e1dbc229e9054850a63357c0a26901b1,

title = "The Open-Access European Prevention of Alzheimer{\textquoteright}s Dementia (EPAD) MRI dataset and processing workflow",

author = "Luigi Lorenzini and Silvia Ingala and Wink, {Alle Meije} and Kuijer, {Joost P.a.} and Viktor Wottschel and Mathijs Dijsselhof and Sudre, {Carole H.} and Sven Haller and Molinuevo, {Jos{\'e} Luis} and Gispert, {Juan Domingo} and Cash, {David M.} and Thomas, {David L.} and Vos, {Sjoerd B.} and Ferran Prados and Jan Petr and Robin Wolz and Alessandro Palombit and Schwarz, {Adam J.} and Ga{\"e}l Ch{\'e}telat and Pierre Payoux and {Di Perri}, Carol and Wardlaw, {Joanna M.} and Frisoni, {Giovanni B.} and Christopher Foley and Fox, {Nick C.} and Craig Ritchie and Cyril Pernet and Adam Waldman and Frederik Barkhof and Mutsaerts, {Henk J.m.m.}",

note = "Funding Information: EPAD is supported by the EU/EFPIA Innovative Medicines Initiative Joint Undertaking EPAD grant agreement 115736. Funding Information: GBF is funded by: A.P.R.A. - Association Suisse pour la Recherche sur la Maladie d{\textquoteright}Alzheimer, Gen{\`e}ve; Fondation Segr{\'e}, Gen{\`e}ve; Ivan Pictet, Gen{\`e}ve; Fondazione Agusta, Lugano; Fondation Chmielewski, Gen{\`e}ve; Swiss National Science Foundation; and VELUX Foundation. Funding Information: DMC is supported by the UK Dementia Research Institute which receives its funding from DRI Ltd, funded by the UK Medical Research Council, Alzheimer{\textquoteright}s Society, and Alzheimer{\textquoteright}s Research UK, as well as Alzheimer's Research UK (ARUK‐PG2017‐1946) and the UCL/UCLH NIHR Biomedical Research Centre. Funding Information: DLT is supported by the UCLH NIHR Biomedical Research Centre, the Wellcome Trust (Centre award 539208), and Alzheimer{\textquoteright}s Research UK (ARUK-NAS2016B-2) Funding Information: JMW is supported by the UK Dementia Research Institute Ltd (funded by the UK MRC, ARUK, and Alzheimer Society) and the Fondation Leducq (16 CVD 05). Funding Information: NCF is supported by the NIHR UCLH Biomedical Research Centre and the UK Dementia Research Institute at UCL Funding Information: This work is part of the EPAD LCS (European Prevention of Alzheimer's Dementia Longitudinal Cohort Study). The authors would like to express their gratitude to the EPAD-LCS participants, without whom this research would have not been possible. EPAD is supported by the EU/EFPIA Innovative Medicines Initiative Joint Undertaking EPAD grant agreement 115736. FB is supported by the NIHR UCLH Biomedical Research Centre, NCF is supported by the NIHR UCLH Biomedical Research Centre and the UK Dementia Research Institute at UCL, DLT is supported by the UCLH NIHR Biomedical Research Centre, the Wellcome Trust (Centre award 539208), and Alzheimer's Research UK (ARUK-NAS2016B-2), DMC is supported by the UK Dementia Research Institute which receives its funding from DRI Ltd, funded by the UK Medical Research Council, Alzheimer's Society, and Alzheimer's Research UK, as well as Alzheimer's Research UK (ARUK‐PG2017‐1946) and the UCL/UCLH NIHR Biomedical Research Centre. GBF is funded by: A.P.R.A. - Association Suisse pour la Recherche sur la Maladie d'Alzheimer, Gen{\`e}ve; Fondation Segr{\'e}, Gen{\`e}ve; Ivan Pictet, Gen{\`e}ve; Fondazione Agusta, Lugano; Fondation Chmielewski, Gen{\`e}ve; Swiss National Science Foundation; and VELUX Foundation. HM is supported by the Dutch Heart Foundation (2020T049), by the Eurostars-2 joint program with co-funding from the European Union Horizon 2020 research and innovation program, provided by the Netherlands Enterprise Agency (RvO), and by the EU Joint Program for Neurodegenerative Disease Research, provided by the Netherlands Organisation for Health Research and Development and Alzheimer Nederland. JMW is supported by the UK Dementia Research Institute Ltd (funded by the UK MRC, ARUK, and Alzheimer Society) and the Fondation Leducq (16 CVD 05). JDG holds the “Ram{\'o}n y Cajal” fellowship RYC-2013-13054. Funding Information: HM is supported by the Dutch Heart Foundation (2020T049), by the Eurostars-2 joint program with co-funding from the European Union Horizon 2020 research and innovation program, provided by the Netherlands Enterprise Agency (RvO), and by the EU Joint Program for Neurodegenerative Disease Research, provided by the Netherlands Organisation for Health Research and Development and Alzheimer Nederland. Publisher Copyright: {\textcopyright} 2022 The Author(s)",

year = "2022",

month = jul,

day = "7",

doi = "10.1016/j.nicl.2022.103106",

language = "English",

volume = "35",

pages = "103106",

journal = "NeuroImage: Clinical",

issn = "2213-1582",

publisher = "Elsevier",

}

Lorenzini, L, Ingala, S, Wink, AM, Kuijer, JPA, Wottschel, V, Dijsselhof, M, Sudre, CH, Haller, S, Molinuevo, JL, Gispert, JD, Cash, DM, Thomas, DL, Vos, SB, Prados, F, Petr, J, Wolz, R, Palombit, A, Schwarz, AJ, Chételat, G, Payoux, P, Di Perri, C, Wardlaw, JM, Frisoni, GB, Foley, C, Fox, NC, Ritchie, C , Pernet, C , Waldman, A, Barkhof, F & Mutsaerts, HJMM 2022, 'The Open-Access European Prevention of Alzheimer’s Dementia (EPAD) MRI dataset and processing workflow', NeuroImage: Clinical, vol. 35, pp. 103106. https://doi.org/10.1016/j.nicl.2022.103106

TY - JOUR

T1 - The Open-Access European Prevention of Alzheimer’s Dementia (EPAD) MRI dataset and processing workflow

AU - Lorenzini, Luigi

AU - Ingala, Silvia

AU - Wink, Alle Meije

AU - Kuijer, Joost P.a.

AU - Wottschel, Viktor

AU - Dijsselhof, Mathijs

AU - Sudre, Carole H.

AU - Haller, Sven

AU - Molinuevo, José Luis

AU - Gispert, Juan Domingo

AU - Cash, David M.

AU - Thomas, David L.

AU - Vos, Sjoerd B.

AU - Prados, Ferran

AU - Petr, Jan

AU - Wolz, Robin

AU - Palombit, Alessandro

AU - Schwarz, Adam J.

AU - Chételat, Gaël

AU - Payoux, Pierre

AU - Di Perri, Carol

AU - Wardlaw, Joanna M.

AU - Frisoni, Giovanni B.

AU - Foley, Christopher

AU - Fox, Nick C.

AU - Ritchie, Craig

AU - Pernet, Cyril

AU - Waldman, Adam

AU - Barkhof, Frederik

AU - Mutsaerts, Henk J.m.m.

N1 - Funding Information: EPAD is supported by the EU/EFPIA Innovative Medicines Initiative Joint Undertaking EPAD grant agreement 115736. Funding Information: GBF is funded by: A.P.R.A. - Association Suisse pour la Recherche sur la Maladie d’Alzheimer, Genève; Fondation Segré, Genève; Ivan Pictet, Genève; Fondazione Agusta, Lugano; Fondation Chmielewski, Genève; Swiss National Science Foundation; and VELUX Foundation. Funding Information: DMC is supported by the UK Dementia Research Institute which receives its funding from DRI Ltd, funded by the UK Medical Research Council, Alzheimer’s Society, and Alzheimer’s Research UK, as well as Alzheimer's Research UK (ARUK‐PG2017‐1946) and the UCL/UCLH NIHR Biomedical Research Centre. Funding Information: DLT is supported by the UCLH NIHR Biomedical Research Centre, the Wellcome Trust (Centre award 539208), and Alzheimer’s Research UK (ARUK-NAS2016B-2) Funding Information: JMW is supported by the UK Dementia Research Institute Ltd (funded by the UK MRC, ARUK, and Alzheimer Society) and the Fondation Leducq (16 CVD 05). Funding Information: NCF is supported by the NIHR UCLH Biomedical Research Centre and the UK Dementia Research Institute at UCL Funding Information: This work is part of the EPAD LCS (European Prevention of Alzheimer's Dementia Longitudinal Cohort Study). The authors would like to express their gratitude to the EPAD-LCS participants, without whom this research would have not been possible. EPAD is supported by the EU/EFPIA Innovative Medicines Initiative Joint Undertaking EPAD grant agreement 115736. FB is supported by the NIHR UCLH Biomedical Research Centre, NCF is supported by the NIHR UCLH Biomedical Research Centre and the UK Dementia Research Institute at UCL, DLT is supported by the UCLH NIHR Biomedical Research Centre, the Wellcome Trust (Centre award 539208), and Alzheimer's Research UK (ARUK-NAS2016B-2), DMC is supported by the UK Dementia Research Institute which receives its funding from DRI Ltd, funded by the UK Medical Research Council, Alzheimer's Society, and Alzheimer's Research UK, as well as Alzheimer's Research UK (ARUK‐PG2017‐1946) and the UCL/UCLH NIHR Biomedical Research Centre. GBF is funded by: A.P.R.A. - Association Suisse pour la Recherche sur la Maladie d'Alzheimer, Genève; Fondation Segré, Genève; Ivan Pictet, Genève; Fondazione Agusta, Lugano; Fondation Chmielewski, Genève; Swiss National Science Foundation; and VELUX Foundation. HM is supported by the Dutch Heart Foundation (2020T049), by the Eurostars-2 joint program with co-funding from the European Union Horizon 2020 research and innovation program, provided by the Netherlands Enterprise Agency (RvO), and by the EU Joint Program for Neurodegenerative Disease Research, provided by the Netherlands Organisation for Health Research and Development and Alzheimer Nederland. JMW is supported by the UK Dementia Research Institute Ltd (funded by the UK MRC, ARUK, and Alzheimer Society) and the Fondation Leducq (16 CVD 05). JDG holds the “Ramón y Cajal” fellowship RYC-2013-13054. Funding Information: HM is supported by the Dutch Heart Foundation (2020T049), by the Eurostars-2 joint program with co-funding from the European Union Horizon 2020 research and innovation program, provided by the Netherlands Enterprise Agency (RvO), and by the EU Joint Program for Neurodegenerative Disease Research, provided by the Netherlands Organisation for Health Research and Development and Alzheimer Nederland. Publisher Copyright: © 2022 The Author(s)

PY - 2022/7/7

Y1 - 2022/7/7

U2 - 10.1016/j.nicl.2022.103106

DO - 10.1016/j.nicl.2022.103106

M3 - Article

SN - 2213-1582

VL - 35

SP - 103106

JO - NeuroImage: Clinical

JF - NeuroImage: Clinical

ER -