The pituitary effects of GnRH

Adam J Pawson, Alan S McNeilly

Research output: Contribution to journalArticlepeer-review

Abstract

Advances in our understanding of the complexity of GnRH actions at the pituitary and the various mechanisms involved in mediating differential LH and FSH biosynthesis and secretion at the gonadotrope, are continually emerging. In this review, we summarise recent studies pertaining to GnRH and GnRH receptor phylogeny, the divergent signalling and trafficking pathways initiated and utilised by GnRH and its receptor, and the pathways that mediate gonadotropin secretion from the gonadotrope.
Original languageEnglish
Pages (from-to)75-94
Number of pages20
JournalAnimal Reproduction Science
Volume88
Issue number1-2
DOIs
Publication statusPublished - 2005

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