The Polyploid Continuum and Landscape of Polyploid Genomic Variation

Polyploid research has traditionally distinguished between autopolyploids and allopolyploids based on evolutionary origins, modes of inheritance, or chromosomal pairing behavior during meiosis. It has long been recognized, however, that a binary classification does not accurately reflect the complexity and diversity inherent to polyploid organisms, and that these definitions may be inadequate to capture biological diversity. Moreover, inferred conditions at polyploid formation are often obscured by numerous post-polyploidy genomic processes, necessitating a temporal perspective on the meaning of polyploid terminology. In this review, we explore the concept of the "polyploid continuum" and highlight the temporal biological fluidity between the classically recognized alternative endpoints of auto- and allopolyploidy. We consider aspects of the polyploid continuum that might meaningfully be evaluated based on different aspects of genetic variation, including at the sequence, structural, and functional levels. We discuss the utility of the polyploid continuum concept and how it might be visualized as a multidimensional landscape of polyploid diversity that at any one time represents a temporal snapshot. This perspective may better reveal the genesis of polyploid diversity in its many dimensions and provide a framework for understanding the dynamic evolutionary processes underpinning polyploid variation.