The prevalence of coexisting mental health conditions in gender diverse autistic people: A systematic review

Ashleigh Simpson, Mikayla Van Rensburg, Ling Ding, Ewelina Rydzewska-Fazekas*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Background

Previous research has highlighted higher prevalence of autism amongst gender diverse individuals compared to cisgender individuals. Both the autistic population, and gender diverse population, have been found to be at an increased risk of developing mental health conditions compared to the general population. However, little is understood about the mental health outcomes of those that are both autistic and gender diverse. Aims: The aims of this review were to assess the mental health outcomes in gender diverse autistic individuals and whether these outcomes were affected by biological sex or age.

Method

A literature review was conducted using the following databases: MEDLINE, PsycINFO, EMBASE and CINAHL. The review was registered with PROSPERO (CRD42023408287). Search terms relating to autism, gender diversity and mental health were used.

Results

12/820 retrieved papers were included in the review. The most common health outcomes studied were depression, anxiety and suicidality. Gender diverse autistic individuals’ mental health was poorer in all 7 studies when comparing to cisgender autistic individuals, in all 8 studies when comparing to gender-diverse non-autistic individuals and in all 6 studies when comparing to cisgender non-autistic individuals.

Conclusion

Gender diverse autistic individuals appear to be particularly vulnerable to experiencing mental health problems, more so than gender diverse individuals and autistic individuals.
Original languageEnglish
Article number102427
Pages (from-to)1-22
Number of pages22
JournalResearch in autism spectrum disorders
Volume116
Early online date7 Jun 2024
DOIs
Publication statusPublished - Aug 2024

Keywords / Materials (for Non-textual outputs)

  • autism
  • gender diverse
  • non-binary
  • transgender
  • depression
  • anxiety

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