Abstract
The acute respiratory distress syndrome (ARDS) represents a form of severe acute inflammatory lung disease. We have previously demonstrated significantly raised interleukin-8 (IL-8) levels in the lungs of at-risk patients that progress to ARDS, and identified the alveolar macrophage as an important source of this chemokine. We wished to extend this study in a well-defined group of patients with major trauma, and to investigate potential mechanisms for rapid intrapulmonary IL-8 generation.
Original language | English |
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Pages (from-to) | 685-97 |
Number of pages | 13 |
Journal | Molecular Medicine |
Volume | 7 |
Issue number | 10 |
Publication status | Published - 2001 |