The release of nitric oxide from S-nitrosothiols promotes angiogenesis

Bahjat Al-Ani; Peter W Hewett; Suborna Ahmed; Melissa Cudmore; Takeshi Fujisawa; Shakil Ahmad; Asif Ahmed

doi:10.1371/journal.pone.0000025

The release of nitric oxide from S-nitrosothiols promotes angiogenesis

Bahjat Al-Ani, Peter W Hewett, Suborna Ahmed, Melissa Cudmore, Takeshi Fujisawa, Shakil Ahmad, Asif Ahmed

Research output: Contribution to journal › Article › peer-review

Abstract

Free nitric oxide (NO) reacts with sulphydryl residues to form S-nitrosothiols, which act as NO reservoirs. We sought to determine whether thiol-preserving agents and antioxidants, such as dithiothreitol (DTT) and vitamin C, induce NO release from S-nitrosylated proteins in endothelial cell cultures to promote angiogenesis.

Original language	English
Pages (from-to)	e25
Journal	PLoS ONE
Volume	1
DOIs	https://doi.org/10.1371/journal.pone.0000025
Publication status	Published - 2006

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10.1371/journal.pone.0000025

The release of nitric oxide from S-nitrosothiols promotes angiogenesis
Copyright: © 2006 Al-Ani et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0000025

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title = "The release of nitric oxide from S-nitrosothiols promotes angiogenesis",

abstract = "Free nitric oxide (NO) reacts with sulphydryl residues to form S-nitrosothiols, which act as NO reservoirs. We sought to determine whether thiol-preserving agents and antioxidants, such as dithiothreitol (DTT) and vitamin C, induce NO release from S-nitrosylated proteins in endothelial cell cultures to promote angiogenesis.",

author = "Bahjat Al-Ani and Hewett, \{Peter W\} and Suborna Ahmed and Melissa Cudmore and Takeshi Fujisawa and Shakil Ahmad and Asif Ahmed",

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AU - Al-Ani, Bahjat

AU - Hewett, Peter W

AU - Ahmed, Suborna

AU - Cudmore, Melissa

AU - Fujisawa, Takeshi

AU - Ahmad, Shakil

AU - Ahmed, Asif

PY - 2006

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AB - Free nitric oxide (NO) reacts with sulphydryl residues to form S-nitrosothiols, which act as NO reservoirs. We sought to determine whether thiol-preserving agents and antioxidants, such as dithiothreitol (DTT) and vitamin C, induce NO release from S-nitrosylated proteins in endothelial cell cultures to promote angiogenesis.

U2 - 10.1371/journal.pone.0000025

DO - 10.1371/journal.pone.0000025

M3 - Article

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SN - 1932-6203

VL - 1

SP - e25

JO - PLoS ONE

JF - PLoS ONE

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The release of nitric oxide from S-nitrosothiols promotes angiogenesis

Abstract

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