@article{1fef68e741ae4ab6a1a900915aa58fb0,
title = "The Rise of Adaptive Platform Trials in Critical Care",
abstract = "As durable learning research systems, adaptive platform trials represent a transformative new approach to accelerating clinical evaluation and discovery in critical care. This Perspective provides a brief introduction to the concept of adaptive platform trials, describes several established and emerging platforms in critical care, and surveys some opportunities and challenges for their implementation and impact.",
author = "{PRACTICAL, PANTHER, TRAITS, INCEPT, and REMAP-CAP investigators} and Bos, {Lieuwe D J} and Carolyn Calfee and Andrea Castellvi-Font and Victoria Cornelius and Derde, {Lennie PG} and Docherty, {Annemarie B} and Eddy Fan and Niall Ferguson and Ewan Goligher and Gordon, {Anthony C} and Anders Granholm and Harhay, {Michael O} and Anna Heath and {Norregaard Kjaer}, Maj-Brit and Lawler, {Patrick R} and Lone, {Nazir I} and McAuley, {Danny F.} and M{\o}ller, {Morten Hylander} and Laveena Munshi and Srinivas Murthy and Nichol, {Alistair D} and Anders Perner and Kiran Reddy and Bram Rochwerg and Kathy Rowan and Sarina Sahetya and Manu Shankar-Hari and Steve Webb and Weir, {Christopher J} and Ryan Zarychanski",
year = "2024",
month = mar,
day = "1",
doi = "10.1164/rccm.202401-0101CP",
language = "English",
volume = "209",
pages = "491--496",
journal = "American Journal of Respiratory and Critical Care Medicine",
issn = "1073-449X",
publisher = "American Thoracic Society",
number = "5",
}