Abstract
The incidence of acute kidney injury (AKI) is increasing. It is now widely accepted that patients surviving an episode of AKI have a significant risk of progression to chronic kidney disease (CKD) and even end-stage renal failure. Zager and colleagues describe the role of endothelin-1 (ET-1) in the progression of AKI to CKD and provide a basis for the potential use of ET receptor antagonists as a therapeutic strategy in AKI.
Original language | English |
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Pages (from-to) | 637-638 |
Number of pages | 2 |
Journal | Kidney International |
Volume | 84 |
Issue number | 4 |
DOIs | |
Publication status | Published - Oct 2013 |
Keywords
- ACUTE KIDNEY INJURY
- DISEASE