The road from AKI to CKD: the role of endothelin

Neeraj Dhaun; David J. Webb

doi:10.1038/ki.2013.158

The road from AKI to CKD: the role of endothelin

Neeraj Dhaun^*, David J. Webb

^*Corresponding author for this work

Research output: Contribution to journal › Editorial › peer-review

Abstract

The incidence of acute kidney injury (AKI) is increasing. It is now widely accepted that patients surviving an episode of AKI have a significant risk of progression to chronic kidney disease (CKD) and even end-stage renal failure. Zager and colleagues describe the role of endothelin-1 (ET-1) in the progression of AKI to CKD and provide a basis for the potential use of ET receptor antagonists as a therapeutic strategy in AKI.

Original language	English
Pages (from-to)	637-638
Number of pages	2
Journal	Kidney International
Volume	84
Issue number	4
DOIs	https://doi.org/10.1038/ki.2013.158
Publication status	Published - Oct 2013

Keywords

ACUTE KIDNEY INJURY
DISEASE

Access to Document

10.1038/ki.2013.158

Cite this

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title = "The road from AKI to CKD: the role of endothelin",

abstract = "The incidence of acute kidney injury (AKI) is increasing. It is now widely accepted that patients surviving an episode of AKI have a significant risk of progression to chronic kidney disease (CKD) and even end-stage renal failure. Zager and colleagues describe the role of endothelin-1 (ET-1) in the progression of AKI to CKD and provide a basis for the potential use of ET receptor antagonists as a therapeutic strategy in AKI.",

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AB - The incidence of acute kidney injury (AKI) is increasing. It is now widely accepted that patients surviving an episode of AKI have a significant risk of progression to chronic kidney disease (CKD) and even end-stage renal failure. Zager and colleagues describe the role of endothelin-1 (ET-1) in the progression of AKI to CKD and provide a basis for the potential use of ET receptor antagonists as a therapeutic strategy in AKI.

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KW - DISEASE

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JF - Kidney International

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