The road from AKI to CKD: the role of endothelin

Neeraj Dhaun*, David J. Webb

*Corresponding author for this work

Research output: Contribution to journalEditorialpeer-review

Abstract

The incidence of acute kidney injury (AKI) is increasing. It is now widely accepted that patients surviving an episode of AKI have a significant risk of progression to chronic kidney disease (CKD) and even end-stage renal failure. Zager and colleagues describe the role of endothelin-1 (ET-1) in the progression of AKI to CKD and provide a basis for the potential use of ET receptor antagonists as a therapeutic strategy in AKI.

Original languageEnglish
Pages (from-to)637-638
Number of pages2
JournalKidney International
Volume84
Issue number4
DOIs
Publication statusPublished - Oct 2013

Keywords

  • ACUTE KIDNEY INJURY
  • DISEASE

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