The STAT3-IL10-IL6 pathway is a novel regulator of macrophage efferocytosis and phenotypic conversion in sterile liver injury

Lara Campana; Philip Starkey Lewis; Antonella Pellicoro; Rebecca Aucott; Janet Man; Eoghan O'Duibhir; Sarah E Mok; Sofia Ferreira-Gonzalez; Eilidh Livingstone; Stephen Greenhalgh; Katherine L Hull; Timothy J. Kendall; Douglas Vernimmen; Neil C. Henderson; Luke Boulter; Christopher D. Gregory; Yi Feng; Stephen M. Anderton; Stuart J. Forbes; John P. Iredale

doi:10.4049/jimmunol.1701247

The STAT3-IL10-IL6 pathway is a novel regulator of macrophage efferocytosis and phenotypic conversion in sterile liver injury

Lara Campana, Philip Starkey Lewis, Antonella Pellicoro, Rebecca Aucott, Janet Man, Eoghan O'Duibhir, Sarah E Mok, Sofia Ferreira-Gonzalez, Eilidh Livingstone, Stephen Greenhalgh, Katherine L Hull, Timothy J. Kendall, Douglas Vernimmen, Neil C. Henderson, Luke Boulter, Christopher D. Gregory, Yi Feng, Stephen M. Anderton, Stuart J. Forbes, John P. Iredale

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	1169-1187
Journal	The Journal of Immunology
Volume	200
Issue number	3
Early online date	22 Jan 2018
DOIs	https://doi.org/10.4049/jimmunol.1701247
Publication status	Published - Feb 2018

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10.4049/jimmunol.1701247

https://europepmc.org/abstract/MED/29263216

A HUB FOR ENGINEERING AND EXPLOITING THE STEM CELL NICHE
Forbes, S.
MRC
1/11/13 → 31/03/18
Project: Research

Stephen Greenhalgh
- Stephen.Greenhalghed.acuk
- Royal (Dick) School of Veterinary Studies - Lecturer in Animal Bioscience
Person: Academic: Research Active
Douglas Vernimmen
- douglas.vernimmenroslin.ed.acuk
- Royal (Dick) School of Veterinary Studies - Group Leader
- Edinburgh Haematopoiesis Network
Person: Academic: Research Active

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Campana, L., Starkey Lewis, P., Pellicoro, A., Aucott, R., Man, J., O'Duibhir, E., Mok, S. E., Ferreira-Gonzalez, S., Livingstone, E., Greenhalgh, S., Hull, K. L., Kendall, T. J., Vernimmen, D., Henderson, N. C., Boulter, L., Gregory, C. D., Feng, Y., Anderton, S. M., Forbes, S. J., & Iredale, J. P. (2018). The STAT3-IL10-IL6 pathway is a novel regulator of macrophage efferocytosis and phenotypic conversion in sterile liver injury. The Journal of Immunology, 200(3), 1169-1187. https://doi.org/10.4049/jimmunol.1701247

@article{c2ad045bf9194eb294d53056c89572c5,

title = "The STAT3-IL10-IL6 pathway is a novel regulator of macrophage efferocytosis and phenotypic conversion in sterile liver injury",

author = "Lara Campana and {Starkey Lewis}, Philip and Antonella Pellicoro and Rebecca Aucott and Janet Man and Eoghan O'Duibhir and Mok, {Sarah E} and Sofia Ferreira-Gonzalez and Eilidh Livingstone and Stephen Greenhalgh and Hull, {Katherine L} and Kendall, {Timothy J.} and Douglas Vernimmen and Henderson, {Neil C.} and Luke Boulter and Gregory, {Christopher D.} and Yi Feng and Anderton, {Stephen M.} and Forbes, {Stuart J.} and Iredale, {John P.}",

year = "2018",

month = feb,

doi = "10.4049/jimmunol.1701247",

language = "English",

volume = "200",

pages = "1169--1187",

journal = "The Journal of Immunology",

issn = "0022-1767",

publisher = "American Association of Immunologists",

number = "3",

}

Campana, L, Starkey Lewis, P, Pellicoro, A , Aucott, R , Man, J, O'Duibhir, E, Mok, SE, Ferreira-Gonzalez, S, Livingstone, E, Greenhalgh, S, Hull, KL, Kendall, TJ , Vernimmen, D , Henderson, NC , Boulter, L , Gregory, CD , Feng, Y, Anderton, SM, Forbes, SJ & Iredale, JP 2018, 'The STAT3-IL10-IL6 pathway is a novel regulator of macrophage efferocytosis and phenotypic conversion in sterile liver injury', The Journal of Immunology, vol. 200, no. 3, pp. 1169-1187. https://doi.org/10.4049/jimmunol.1701247

TY - JOUR

T1 - The STAT3-IL10-IL6 pathway is a novel regulator of macrophage efferocytosis and phenotypic conversion in sterile liver injury

AU - Campana, Lara

AU - Starkey Lewis, Philip

AU - Pellicoro, Antonella

AU - Aucott, Rebecca

AU - Man, Janet

AU - O'Duibhir, Eoghan

AU - Mok, Sarah E

AU - Ferreira-Gonzalez, Sofia

AU - Livingstone, Eilidh

AU - Greenhalgh, Stephen

AU - Hull, Katherine L

AU - Kendall, Timothy J.

AU - Vernimmen, Douglas

AU - Henderson, Neil C.

AU - Boulter, Luke

AU - Gregory, Christopher D.

AU - Feng, Yi

AU - Anderton, Stephen M.

AU - Forbes, Stuart J.

AU - Iredale, John P.

PY - 2018/2

Y1 - 2018/2

U2 - 10.4049/jimmunol.1701247

DO - 10.4049/jimmunol.1701247

M3 - Article

SN - 0022-1767

VL - 200

SP - 1169

EP - 1187

JO - The Journal of Immunology

JF - The Journal of Immunology

IS - 3

ER -

The STAT3-IL10-IL6 pathway is a novel regulator of macrophage efferocytosis and phenotypic conversion in sterile liver injury

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A HUB FOR ENGINEERING AND EXPLOITING THE STEM CELL NICHE

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Stephen Greenhalgh

Douglas Vernimmen

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