The Third International Stroke Trial: Thrombolysis (IST-3) in Poland: are we recruiting the right patients?

Anna Członkowska, Adam Kobayashi, Peter Sandercock, Richard Lindley, Maria Barańska-Gierszczak, Stephanie Lewis

Research output: Contribution to journalArticlepeer-review

Abstract

Recombinant tissue plasminogen activator (rt-PA, alteplase) for acute ischaemic stroke was provisionally granted in Europe in 2002 and the granted license excluded many patient groups from treatment. Uncertainties about the balance of risk and benefit in several categories of patients still remain. The aim of the Third International Stroke Trial (IST-3) is to determine whether more patients can benefit from treatment. We present the rationale for the study and compare the characteristics of patients recruited to the study in Poland with those recruited in other countries.
Original languageEnglish
Pages (from-to)228-35
Number of pages8
JournalNeurologia i neurochirurgia polska
Volume43
Issue number3
Publication statusPublished - 2009

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