The Transcription Factor STAT-1 Couples Macrophage Synthesis of 25-Hydroxycholesterol to the Interferon Antiviral Response

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• Finished

  SynthSys; formerly CSBE: Centre for Systems Biology at Edinburgh

  Millar, A. (Principal Investigator), Beggs, J. (Co-investigator), Ghazal, P. (Co-investigator), Goryanin, I. (Co-investigator), Hillston, J. (Co-investigator), Plotkin, G. (Co-investigator), Tollervey, D. (Co-investigator), Walton, A. (Co-investigator) & Robertson, K. (Researcher)

  BBSRC

  8/01/07 → 31/12/12

  Project: Research

  • Circadian Rhythm 100%
  • Arabidopsis 41%
  • Gene Expression 36%
  • Rhythm 33%
  • Process Algebra 28%

• Molecular determinants of virus re-activation, latency and pathogenesis.

  Ghazal, P. (Principal Investigator)

  UK-based charities

  1/10/03 → 30/09/08

  Project: Research

  • Murine Cytomegalovirus 100%
  • Macrophage 91%
  • Interferon Type I 86%
  • Antiviral Immunity 86%
  • Enhancer Region 86%